Balancing risks and benefits of cannabis use: umbrella review of meta-analyses of randomised controlled trials and observational studies
Objective To systematically assess credibility and certainty of associations between
cannabis, cannabinoids, and cannabis based medicines and human health, from …
cannabis, cannabinoids, and cannabis based medicines and human health, from …
Cannabis Bioactive Compound-Based Formulations: New Perspectives for the Management of Orofacial Pain
G Crescente, G Minervini, C Spagnuolo, S Moccia - Molecules, 2022 - mdpi.com
The management of orofacial pain to alleviate the quality of life of affected patients is
becoming increasingly challenging for scientific research and healthcare professionals …
becoming increasingly challenging for scientific research and healthcare professionals …
An overview on synthetic and biological activities of cannabidiol (CBD) and its derivatives
X Wang, H Zhang, Y Liu, Y Xu, B Yang, H Li… - Bioorganic Chemistry, 2023 - Elsevier
Cannabidiol is a class of non-psychoactive plant cannabinoids derived from cannabis
plants. Currently, Epidiolex (Cannabidiol) has been approved by the FDA for the treatment of …
plants. Currently, Epidiolex (Cannabidiol) has been approved by the FDA for the treatment of …
Cannabis constituents for chronic neuropathic pain; reconciling the clinical and animal evidence
E Sokolaj, N Assareh, K Anderson… - Journal of …, 2023 - Wiley Online Library
Chronic neuropathic pain is a debilitating pain syndrome caused by damage to the nervous
system that is poorly served by current medications. Given these problems, clinical studies …
system that is poorly served by current medications. Given these problems, clinical studies …
Combinations of Cannabidiol and Δ9-Tetrahydrocannabinol in Reducing Chemotherapeutic Induced Neuropathic Pain
DE Sepulveda, KE Vrana, NM Graziane… - Biomedicines, 2022 - mdpi.com
Neuropathic pain is a condition that impacts a substantial portion of the population and is
expected to affect a larger percentage in the future. This type of pain is poorly managed by …
expected to affect a larger percentage in the future. This type of pain is poorly managed by …
A brief review on the novel therapies for painful diabetic neuropathy
Abstract Purpose of Review Almost half of people diagnosed with diabetes mellitus will
develop painful diabetic neuropathy (PDN), a condition greatly impacting quality of life with …
develop painful diabetic neuropathy (PDN), a condition greatly impacting quality of life with …
URB937 prevents the development of mechanical allodynia in male rats with trigeminal neuralgia
C Demartini, R Greco, AM Zanaboni, M Francavilla… - Pharmaceuticals, 2023 - mdpi.com
Cannabinoids are proposed for alleviating neuropathic pain, but their use is limited by
cannabimimetic side effects. The inhibition of the fatty acid amide hydrolase (FAAH), the …
cannabimimetic side effects. The inhibition of the fatty acid amide hydrolase (FAAH), the …
Phytocannabinoids for the Treatment of Neuropathic Pain: A Scoping Review of Randomised Controlled Trials Published Between 2012 and 2023
M Lewis, S Baroutian, SM Hanning - Current Pain and Headache Reports, 2024 - Springer
Abstract Purpose of Review Neuropathic pain (NP) remains a challenge to treat, with 50% of
patients experiencing limited efficacy from current treatments. Medicinal cannabis, which …
patients experiencing limited efficacy from current treatments. Medicinal cannabis, which …
Topical cannabidiol is well tolerated in individuals with a history of elite physical performance and chronic lower extremity pain
N Hall, B James, MAN Bhuiyan, E Crane… - Journal of Cannabis …, 2023 - Springer
Introduction Cannabidiol (CBD) is a potential therapeutic for pain management. Yet, there
exists a dearth of studies of its tolerability and efficacy, especially in special populations …
exists a dearth of studies of its tolerability and efficacy, especially in special populations …
Systematic review and meta-analysis seem to indicate that cannabinoids for chronic primary pain treatment have limited benefit
R Giossi, F Carrara, M Padroni, MC Bilancio… - Pain and Therapy, 2022 - Springer
Abstract Introduction The IASP ICD-11 chronic primary pain (CPP) definition includes 19
different painful conditions. In recent years, interest in the potential role of cannabinoids in …
different painful conditions. In recent years, interest in the potential role of cannabinoids in …