Rational nanomedicine design enhances clinically physical Treatment‐Inspired or combined immunotherapy

Q Liu, W Zhang, R Jiao, Z Lv, X Lin, Y Xiao… - Advanced …, 2022 - Wiley Online Library
Independent of tumor type and non‐invasive or minimally‐invasive feature, current physical
treatments including ultrasound therapy, microwave ablation (MWA), and radiofrequency …

Combinatory local ablation and immunotherapies for hepatocellular carcinoma: Rationale, efficacy, and perspective

S Chen, X Zeng, T Su, H Xiao, M Lin, Z Peng… - Frontiers in …, 2022 - frontiersin.org
Hepatocellular carcinoma (HCC) is the leading cause of cancer-related death worldwide.
Local ablation, such as radiofrequency ablation, microwave ablation, cryoablation and …

Eliminating METTL1‐mediated accumulation of PMN‐MDSCs prevents hepatocellular carcinoma recurrence after radiofrequency ablation

X Zeng, G Liao, S Li, H Liu, X Zhao, S Li, K Lei… - Hepatology, 2023 - journals.lww.com
Conclusions: Our study sheds light on the pivotal role of METTL1 in modulating an
immunosuppressive microenvironment and demonstrated that interrupting METTL1‐TGF‐β2 …

The synergistic effect of interventional locoregional treatments and immunotherapy for the treatment of hepatocellular carcinoma

N Brandi, M Renzulli - International Journal of Molecular Sciences, 2023 - mdpi.com
Immunotherapy has remarkably revolutionized the management of advanced HCC and
prompted clinical trials, with therapeutic agents being used to selectively target immune cells …

Immunotherapies for hepatocellular carcinoma

JKH Liu, AF Irvine, RL Jones, A Samson - Cancer Medicine, 2022 - Wiley Online Library
Cases of hepatocellular carcinoma (HCC) are rapidly rising. This is particularly the case in
the Western world, as a result of increasing rates of chronic liver disease, secondary to …

Immunotherapy Plus Locoregional Therapy Leading to Curative-Intent Hepatectomy in HCC: Proof of Concept Producing Durable Survival Benefits Detectable with …

R Raj, CJ Wehrle, N Aykun, H Stitzel, WW Ma… - Cancers, 2023 - mdpi.com
Simple Summary Immunotherapy is emerging as an improved systemic treatment for select
patients with advanced unresectable hepatocellular carcinoma. An objective response is …

Synergetic thermal therapy for cancer: state-of-the-art and the future

Q Dai, B Cao, S Zhao, A Zhang - Bioengineering, 2022 - mdpi.com
As a safe and minimal-invasive modality, thermal therapy has become an effective treatment
in cancer treatment. Other than killing the tumor cells or destroying the tumor entirely, the …

[HTML][HTML] A multidisciplinary approach with immunotherapies for advanced hepatocellular carcinoma

YR Lee - Journal of Liver Cancer, 2023 - synapse.koreamed.org
Hepatocellular carcinoma (HCC) is a highly aggressive disease that is usually diagnosed at
an advanced stage. Advanced HCC has limited treatment options and often has a poor …

Immunotherapy for Advanced Hepatocellular Carcinoma-a Large Tertiary Center Experience

R Raj, N Aykun, CJ Wehrle, M Maspero… - Journal of …, 2023 - Elsevier
Introduction Combination of immune-checkpoint inhibitor (ICI) and vascular endothelial
growth factor (VEGF) antagonist has become the first line systemic treatment for advanced …

Progress of immune checkpoint inhibitors in the treatment of advanced hepatocellular carcinoma

T Liu, G Meng, S Ma, J You, L Yu, R He… - Frontiers in …, 2024 - frontiersin.org
Among primary liver cancers, hepatocellular carcinoma is the most common pathological
type. Its onset is insidious, and most patients have no obvious discomfort in the early stage …