The role of microRNA in rheumatoid arthritis and other autoimmune diseases
V Furer, JD Greenberg, M Attur, SB Abramson… - Clinical …, 2010 - Elsevier
MicroRNAs (miRNAs) represent a class of non-coding RNA molecules playing pivotal roles
in cellular and developmental processes. miRNAs modulate the expression of multiple …
in cellular and developmental processes. miRNAs modulate the expression of multiple …
Reduced apoptosis correlates with enhanced autophagy in synovial tissues of rheumatoid arthritis
K Xu, P Xu, JF Yao, YG Zhang, W Hou, SM Lu - Inflammation Research, 2013 - Springer
Objective Defective apoptosis contributes to the massive synovial hyperplasia in rheumatoid
arthritis (RA), but the mechanism is largely unknown. To investigate the reasons for the …
arthritis (RA), but the mechanism is largely unknown. To investigate the reasons for the …
Galectin 3 induces a distinctive pattern of cytokine and chemokine production in rheumatoid synovial fibroblasts via selective signaling pathways
A Filer, M Bik, GN Parsonage, J Fitton… - … : Official Journal of …, 2009 - Wiley Online Library
Objective High expression of galectin 3 at sites of joint destruction in rheumatoid arthritis
(RA) suggests that galectin 3 plays a role in RA pathogenesis. Previous studies have …
(RA) suggests that galectin 3 plays a role in RA pathogenesis. Previous studies have …
Autotaxin, a secreted lysophospholipase D, as a promising therapeutic target in chronic inflammation and cancer
Autotaxin (ATX) is a member of the nucleotide pyrophosphatase/phosphodiesterase family
of ectoenzymes that hydrolyzes phosphodiester bonds of various nucleotides. It possesses …
of ectoenzymes that hydrolyzes phosphodiester bonds of various nucleotides. It possesses …
Rheumatoid synovial fibroblasts differentiate into distinct subsets in the presence of cytokines and cartilage
Background We investigated two distinct synovial fibroblast populations that were located
preferentially in the lining or sub-lining layers and defined by their expression of either …
preferentially in the lining or sub-lining layers and defined by their expression of either …
Synovial cellular and molecular markers in rheumatoid arthritis
The profound alterations in the structure, cellular composition, and function of synovial tissue
in rheumatoid arthritis (RA) are the basis for the persistent inflammation and cumulative joint …
in rheumatoid arthritis (RA) are the basis for the persistent inflammation and cumulative joint …
The role of marine n-3 polyunsaturated fatty acids in inflammatory-based disease: the case of rheumatoid arthritis
C Parolini - Marine Drugs, 2023 - mdpi.com
Inflammation is a conserved process that involves the activation of immune and non-immune
cells aimed at protecting the host from bacteria, viruses, toxins and injury. However …
cells aimed at protecting the host from bacteria, viruses, toxins and injury. However …
Swertiamarin attenuates inflammation mediators via modulating NF-κB/I κB and JAK2/STAT3 transcription factors in adjuvant induced arthritis
Rheumatoid arthritis (RA) is an autoimmune and chronic inflammatory disease that leads to
pannus formation followed by severe joint destruction, characterized by synovial …
pannus formation followed by severe joint destruction, characterized by synovial …
Inhibiting peripheral and central MAO-B ameliorates joint inflammation and cognitive impairment in rheumatoid arthritis
Rheumatoid arthritis (RA) is an autoimmune disorder characterized by chronic inflammation
and the destruction of joints and systemic organs. RA is commonly accompanied by …
and the destruction of joints and systemic organs. RA is commonly accompanied by …
Bruton's tyrosine kinase is involved in miR-346-related regulation of IL-18 release by lipopolysaccharide-activated rheumatoid fibroblast-like synoviocytes
G Alsaleh, G Suffert, N Semaan, T Juncker… - The Journal of …, 2009 - journals.aai.org
MicroRNAs (miRNAs) have emerged as key players in the regulation of expression of target
mRNAs expression. They have been associated with diverse biological processes, and …
mRNAs expression. They have been associated with diverse biological processes, and …