Joint location–specific JAK‐STAT signaling in rheumatoid arthritis fibroblast‐like synoviocytes
D Hammaker, G Nygaard, A Kuhs, R Ai… - ACR open …, 2019 - Wiley Online Library
Objective Rheumatoid arthritis (RA) fibroblast‐like synoviocytes (FLS) derived from hip and
knee have distinctive DNA methylation and transcriptome patterns in interleukin (IL)‐6 …
knee have distinctive DNA methylation and transcriptome patterns in interleukin (IL)‐6 …
Synovial fluid interleukin levels cannot distinguish between prosthetic joint infection and active rheumatoid arthritis after hip or knee arthroplasty
L Qin, C Du, J Yang, H Wang, X Su, L Wei, C Zhao… - Diagnostics, 2022 - mdpi.com
Inflammatory arthritis affects the level of synovial inflammatory factors, which makes it more
difficult to diagnose prosthetic joint infection (PJI) patients with inflammatory arthritis. The …
difficult to diagnose prosthetic joint infection (PJI) patients with inflammatory arthritis. The …
Swertiamarin ameliorates inflammation and osteoclastogenesis intermediates in IL-1β induced rat fibroblast-like synoviocytes
S Saravanan, VI Hairul Islam… - Inflammation …, 2014 - Springer
Objective and design Rheumatoid arthritis is a chronic inflammatory and autoimmune
disease that leads to aggressive joint cartilage and bone destruction. Swertiamarin is a …
disease that leads to aggressive joint cartilage and bone destruction. Swertiamarin is a …
A protocol for the culture and isolation of murine synovial fibroblasts
J Zhao, Q Ouyang, Z Hu, Q Huang… - Biomedical …, 2016 - spandidos-publications.com
The culture of synovial fibroblasts (SFs) is one of the most effective tools for investigating the
pathology and physiology of synovial tissues and should prove useful for identifying the …
pathology and physiology of synovial tissues and should prove useful for identifying the …
Crosstalk between FLS and chondrocytes is regulated by HIF-2α-mediated cytokines in arthritis
YH Huh, G Lee, WH Song, JT Koh… - Experimental & molecular …, 2015 - nature.com
Rheumatoid arthritis (RA) and osteoarthritis (OA), two common types of arthritis, affect the
joints mainly by targeting the synovium and cartilage. Increasing evidence indicates that a …
joints mainly by targeting the synovium and cartilage. Increasing evidence indicates that a …
Divulging the intricacies of crosstalk between NF-kB and Nrf-2/Keap1 pathway in the treatment of arthritis by dimethyl fumarate
MA Khan, G Rabbani, J Aggarawal… - Applied Biochemistry and …, 2023 - Springer
The aim of this study was to examine the hypothesis that use of dimethyl fumarate (DMF)
may mitigate arthritic symptoms in collagen-induced arthritis (CIA) rats through activation of …
may mitigate arthritic symptoms in collagen-induced arthritis (CIA) rats through activation of …
Multiplex cytokine analysis of aqueous humor in juvenile idiopathic arthritis-associated anterior uveitis with or without secondary glaucoma
D Bauer, M Kasper, K Walscheid, JM Koch… - Frontiers in …, 2018 - frontiersin.org
Patients with juvenile idiopathic arthritis often develop chronic anterior uveitis (JIAU). JIAU
patients possess a particularly high risk for developing secondary glaucoma when …
patients possess a particularly high risk for developing secondary glaucoma when …
Structural cell heterogeneity underlies the differential contribution of IL-17A, IL-17F and IL-23 to joint versus skin chronic inflammation
M Robert, P Miossec - Autoimmunity Reviews, 2024 - Elsevier
The current therapeutic strategy used in immune-mediated inflammatory diseases (IMIDs)
primarily targets immune cells or associated-pathways. However, recent evidence suggests …
primarily targets immune cells or associated-pathways. However, recent evidence suggests …
[HTML][HTML] Altered expression of microRNA-23a in psoriatic arthritis modulates synovial fibroblast pro-inflammatory mechanisms via phosphodiesterase 4B
SM Wade, M Trenkmann, T McGarry, M Canavan… - Journal of …, 2019 - Elsevier
Objectives To investigate the functional role of miR-23a in synovial fibroblasts (SFC)
activation in psoriatic arthritis (PsA). Methods Differential expression of the miR-23a-27a-24 …
activation in psoriatic arthritis (PsA). Methods Differential expression of the miR-23a-27a-24 …
DNA methylation-governed gene expression in autoimmune arthritis
B Brandt, S Rashidiani, Á Bán, TA Rauch - International journal of …, 2019 - mdpi.com
Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease hallmarked by
progressive and irreversible joint destruction. RA pathogenesis is a T cell-regulated and B …
progressive and irreversible joint destruction. RA pathogenesis is a T cell-regulated and B …