Psychotic depression was initially considered to be at one end of a continuum of severity of
major depression. Subsequent experience demonstrated that psychosis is an independent …

Background Completed suicide is a major cause of death in bipolar disorder (BD) patients.
Objective The aim of this paper is to provide an overall review of the existing literature of …

Suicide is a major public health problem in the WHO European Region accounting for over
150,000 deaths per year. Suicidal crisis: Acute intervention should start immediately in order …

Discriminating depressive episodes of bipolar disorder (BD) from major depressive disorder
(MDD) is a major clinical challenge. Recently, gut microbiome alterations are implicated in …

Unipolar and bipolar depressive episodes have a similar clinical presentation that suggests
common dysfunction of the brain's reward system. Here, we evaluated the relationship of …

Objective: This study estimated the risk of recurrence of mood episodes among women with
a history of bipolar disorder who continued or discontinued treatment with mood stabilizers …

Psychosocial issues are an understudied yet important concern in the overall health of
hemodialysis (HD) patients. Stress is a concomitant of chronic illness and its treatment, and …

Disruptions in circadian rhythms have been described in mood disorders (MD), but the
involvement of genetic variation in genes pertaining to the molecular circadian machinery in …

Objective: Little is known about how often bipolar depressive episodes are accompanied by
subsyndromal manic symptoms in bipolar I and II disorders. The authors sought to determine …

BACKGROUND: The nosologic status of agitated depression is unresolved. Are they
unipolar (UP) or bipolar (BP)? Are they mixed states? Even more controversial is the notion …