[HTML][HTML] Lead (Pb) and neurodevelopment: A review on exposure and biomarkers of effect (BDNF, HDL) and susceptibility

C Gundacker, M Forsthuber, T Szigeti, R Kakucs… - International Journal of …, 2021 - Elsevier
Lead (Pb) is a ubiquitous environmental pollutant and a potent toxic compound. Humans are
exposed to Pb through inhalation, ingestion, and skin contact via food, water, tobacco …

[HTML][HTML] Epigenetic modification impacting brain functions: Effects of physical activity, micronutrients, caffeine, toxins, and addictive substances

R Mallick, AK Duttaroy - Neurochemistry International, 2023 - Elsevier
Abstract Changes in gene expression are involved in many brain functions. Epigenetic
processes modulate gene expression by histone modification and DNA methylation or RNA …

Molecular mechanisms of lead neurotoxicity

MB Virgolini, M Aschner - Advances in neurotoxicology, 2021 - Elsevier
Abstract Lead (Pb 2+) is a non-essential metal with numerous industrial applications that
have led to its ubiquity in the environment. Thus, not only occupational-exposed individuals' …

Health repercussions of environmental exposure to lead: Methylation perspective

SS Shiek, MS Mani, SP Kabekkodu, HS Dsouza - Toxicology, 2021 - Elsevier
Lead (Pb) exposure has been a major public health concern for a long time now due to its
permanent adverse effects on the human body. The process of lead toxicity has still not been …

Therapeutic effects of gallic acid in regulating senescence and diabetes; an in vitro study

M Rahimifard, M Baeeri, H Bahadar, S Moini-Nodeh… - Molecules, 2020 - mdpi.com
Gallic acid (GA), a plant-derived ubiquitous secondary polyphenol metabolite, can be a
useful dietary supplement. This in vitro study's primary purpose was to assess the anti-aging …

Combined exposure to formaldehyde and PM2. 5: Hematopoietic toxicity and molecular mechanism in mice

J Ge, H Yang, X Lu, S Wang, Y Zhao, J Huang… - Environment …, 2020 - Elsevier
Abstract PM 2.5 and formaldehyde (FA) are major outdoor and indoor air pollutants in China,
respectively, and both are known to be harmful to human health and to be carcinogenic. Of …

Metal-induced oxidative stress: an evidence-based update of advantages and disadvantages

M Khalid, S Hassani, M Abdollahi - Current opinion in toxicology, 2020 - Elsevier
Metals are well distributed in our ecosystem and have several advantages and
disadvantages. Some are well known for inducing oxidative stress by disturbing the cellular …

Adaptive epigenetic response of glutathione (GSH)-related genes against lead (Pb)-induced toxicity, in individuals chronically exposed to the metal

PP Devóz, MB Dos Reis, WR Gomes, FT Maraslis… - Chemosphere, 2021 - Elsevier
It is well known that one of the most outstanding adverse effects related to lead (Pb)
exposure is oxidative stress; moreover, recent findings suggest that disturbances of the …

Association of urinary heavy metal combined exposure with periodontitis among US adults from NHANES 2011–2014

ZH Li, J Li, YC Mao, JW Zhao, HY Hu, S Zhang… - … Science and Pollution …, 2023 - Springer
Some heavy metals are associated with periodontitis; whereas most of these associations
have focused on individual metal, there are no specific studies on the effects of combined …

Effects of low lead exposure on sperm quality and sperm DNA methylation in adult men

T Zhang, YF Ru, B Wu, H Dong, L Chen, J Zheng, J Li… - Cell & bioscience, 2021 - Springer
Abstract Instruction Lead (Pb) exposure is a risk factor for male infertility, but the epigenetic
changes in sperm DNAattributable to lead exposure is poorly defined. Methods In this study …