Progress in stem cell therapy for spinal cord injury

L Gao, Y Peng, W Xu, P He, T Li, X Lu… - Stem Cells …, 2020 - Wiley Online Library
Background. Spinal cord injury (SCI) is one of the serious neurological diseases that occur
in young people with high morbidity and disability. However, there is still a lack of effective …

Regenerative therapies for spinal cord injury

N Ashammakhi, HJ Kim, A Ehsanipour… - … Engineering Part B …, 2019 - liebertpub.com
Spinal cord injury (SCI) is a serious problem that primarily affects younger and middle-aged
adults at its onset. To date, no effective regenerative treatment has been developed. Over …

[HTML][HTML] Crosstalk between stem cell and spinal cord injury: pathophysiology and treatment strategies

A Shao, S Tu, J Lu, J Zhang - Stem cell research & therapy, 2019 - Springer
The injured spinal cord is difficult to repair and regenerate. Traditional treatments are not
effective. Stem cells are a type of cells that have the potential to differentiate into various …

Spinal interneurons as gatekeepers to neuroplasticity after injury or disease

LV Zholudeva, VE Abraira… - Journal of …, 2021 - Soc Neuroscience
Spinal interneurons are important facilitators and modulators of motor, sensory, and
autonomic functions in the intact CNS. This heterogeneous population of neurons is now …

Hydroxyapatite nanorods function as safe and effective growth factors regulating neural differentiation and neuron development

M Hao, Z Zhang, C Liu, Y Tian, J Duan, J He… - Advanced …, 2021 - Wiley Online Library
Neural stem cell (NSC) transplantation is one of the most promising therapeutic strategies
for neurodegenerative diseases. However, the slow spontaneous differentiation of NSCs …

Advanced functional biomaterials for stem cell delivery in regenerative engineering and medicine

X Wang, N Rivera‐Bolanos, B Jiang… - Advanced Functional …, 2019 - Wiley Online Library
Stem cell–based therapies can potentially regenerate many types of tissues and organs,
thereby providing solutions to a variety of diseases and injuries. However, acute cell death …

The efficacy and safety of mesenchymal stem cell transplantation for spinal cord injury patients: a meta-analysis and systematic review

P Xu, X Yang - Cell transplantation, 2019 - journals.sagepub.com
Spinal cord injury (SCI) is a devastating disease, with a high rate of disability. In this meta-
analysis, we aimed to comprehensively assess the efficacy and safety of mesenchymal stem …

[HTML][HTML] Physical and biological engineering of polymer scaffolds to potentiate repair of spinal cord injury

Y Luo, F Xue, K Liu, B Li, C Fu, J Ding - Materials & Design, 2021 - Elsevier
Although the mortality rates of patients suffering from spinal cord injury (SCI) have
decreased as the modalities of clinical therapy have been improved, the recovery of motor …

[HTML][HTML] The temporal pattern, flux, and function of autophagy in spinal cord injury

K Zhou, CA Sansur, H Xu, X Jia - International journal of molecular …, 2017 - mdpi.com
Previous studies have indicated that autophagy plays a critical role in spinal cord injury
(SCI), including traumatic spinal cord injury (TSCI) and ischemia-reperfusion spinal cord …

[HTML][HTML] Recent advances for using human induced-pluripotent stem cells as pain-in-a-dish models of neuropathic pain

JIR Labau, M Andelic, CG Faber, SG Waxman… - Experimental …, 2022 - Elsevier
Neuropathic pain is amongst the most common non-communicable disorders and the poor
effectiveness of current treatment is an unmet need. Although pain is a universal experience …