Progress in stem cell therapy for spinal cord injury
L Gao, Y Peng, W Xu, P He, T Li, X Lu… - Stem Cells …, 2020 - Wiley Online Library
Background. Spinal cord injury (SCI) is one of the serious neurological diseases that occur
in young people with high morbidity and disability. However, there is still a lack of effective …
in young people with high morbidity and disability. However, there is still a lack of effective …
Regenerative therapies for spinal cord injury
Spinal cord injury (SCI) is a serious problem that primarily affects younger and middle-aged
adults at its onset. To date, no effective regenerative treatment has been developed. Over …
adults at its onset. To date, no effective regenerative treatment has been developed. Over …
[HTML][HTML] Crosstalk between stem cell and spinal cord injury: pathophysiology and treatment strategies
A Shao, S Tu, J Lu, J Zhang - Stem cell research & therapy, 2019 - Springer
The injured spinal cord is difficult to repair and regenerate. Traditional treatments are not
effective. Stem cells are a type of cells that have the potential to differentiate into various …
effective. Stem cells are a type of cells that have the potential to differentiate into various …
Spinal interneurons as gatekeepers to neuroplasticity after injury or disease
LV Zholudeva, VE Abraira… - Journal of …, 2021 - Soc Neuroscience
Spinal interneurons are important facilitators and modulators of motor, sensory, and
autonomic functions in the intact CNS. This heterogeneous population of neurons is now …
autonomic functions in the intact CNS. This heterogeneous population of neurons is now …
Hydroxyapatite nanorods function as safe and effective growth factors regulating neural differentiation and neuron development
Neural stem cell (NSC) transplantation is one of the most promising therapeutic strategies
for neurodegenerative diseases. However, the slow spontaneous differentiation of NSCs …
for neurodegenerative diseases. However, the slow spontaneous differentiation of NSCs …
Advanced functional biomaterials for stem cell delivery in regenerative engineering and medicine
Stem cell–based therapies can potentially regenerate many types of tissues and organs,
thereby providing solutions to a variety of diseases and injuries. However, acute cell death …
thereby providing solutions to a variety of diseases and injuries. However, acute cell death …
The efficacy and safety of mesenchymal stem cell transplantation for spinal cord injury patients: a meta-analysis and systematic review
P Xu, X Yang - Cell transplantation, 2019 - journals.sagepub.com
Spinal cord injury (SCI) is a devastating disease, with a high rate of disability. In this meta-
analysis, we aimed to comprehensively assess the efficacy and safety of mesenchymal stem …
analysis, we aimed to comprehensively assess the efficacy and safety of mesenchymal stem …
[HTML][HTML] Physical and biological engineering of polymer scaffolds to potentiate repair of spinal cord injury
Y Luo, F Xue, K Liu, B Li, C Fu, J Ding - Materials & Design, 2021 - Elsevier
Although the mortality rates of patients suffering from spinal cord injury (SCI) have
decreased as the modalities of clinical therapy have been improved, the recovery of motor …
decreased as the modalities of clinical therapy have been improved, the recovery of motor …
[HTML][HTML] The temporal pattern, flux, and function of autophagy in spinal cord injury
Previous studies have indicated that autophagy plays a critical role in spinal cord injury
(SCI), including traumatic spinal cord injury (TSCI) and ischemia-reperfusion spinal cord …
(SCI), including traumatic spinal cord injury (TSCI) and ischemia-reperfusion spinal cord …
[HTML][HTML] Recent advances for using human induced-pluripotent stem cells as pain-in-a-dish models of neuropathic pain
Neuropathic pain is amongst the most common non-communicable disorders and the poor
effectiveness of current treatment is an unmet need. Although pain is a universal experience …
effectiveness of current treatment is an unmet need. Although pain is a universal experience …