Maternal metabolic health and fertility: we should not only care about but also for the oocyte!

J Leroy, B Meulders, K Moorkens… - Reproduction …, 2022 - CSIRO Publishing
Metabolic disorders due to obesity and unhealthy lifestyle directly alter the oocyte's
microenvironment and impact oocyte quality. Oxidative stress and mitochondrial dysfunction …

[HTML][HTML] Age-dependent metabolomic profile of the follicular fluids from women undergoing assisted reproductive technology treatment

Y Huang, M Tu, Y Qian, J Ma, L Chen, Y Liu… - Frontiers in …, 2022 - frontiersin.org
Female fertility declines with age, and this natural variation culminates in reproductive
senescence. Human follicular fluids are rich in low-molecular weight metabolites which are …

[HTML][HTML] Metabolic signatures in human follicular fluid identify lysophosphatidylcholine as a predictor of follicular development

J Yang, Y Li, S Li, Y Zhang, R Feng, R Huang… - Communications …, 2022 - nature.com
In order to investigate the metabolic characteristics of human follicular fluid (FF) and to
reveal potential metabolic predictors of follicular development (FD) with clinical implications …

[HTML][HTML] Integrated proteomic and metabolomic analyses of chicken ovary revealed the crucial role of lipoprotein lipase on lipid metabolism and steroidogenesis …

Z Cui, Z Ning, X Deng, X Du, FK Amevor, L Liu… - Frontiers in …, 2022 - frontiersin.org
During sexual maturation and ovulatory cycle in chickens, ovaries undergo dynamic
morphological and functional changes. The aim of this study was to evaluate the integrated …

Effects of environmentally relevant concentrations of niclosamide on lipid metabolism and steroid hormone synthesis in adult female zebrafish

X Chen, S Yang, B Zhu, M Zhang, N Zheng… - Science of the Total …, 2024 - Elsevier
Niclosamide (NIC) is a commonly used molluscicide that reportedly disrupts the endocrine
system and may lead to lipid metabolism disorders. However, few studies have investigated …

[HTML][HTML] Identification of Candidate Salivary, Urinary and Serum Metabolic Biomarkers for High Litter Size Potential in Sows (Sus scrofa)

L Fletcher, N Akhtar, X Zhan, M Jafarikia, BP Sullivan… - Metabolites, 2022 - mdpi.com
The selection of sows that are reproductively fit and produce large litters of piglets is
imperative for success in the pork industry. Currently, low heritability of reproductive and …

[HTML][HTML] The influence of male and female overweight/obesity on IVF outcomes: a cohort study based on registration in Western China

X Liu, S Shi, J Sun, Y He, Z Zhang, J Xing, T Chong - Reproductive Health, 2023 - Springer
Background Overweight/obesity can affect fertility, increase the risk of pregnancy
complications, and affect the outcome of assisted reproductive technology (ART). However …

[HTML][HTML] Lipidomics analysis of human follicular fluid form normal-weight patients with polycystic ovary syndrome: a pilot study

Y Ban, H Ran, Y Chen, L Ma - Journal of Ovarian Research, 2021 - Springer
Background The polycystic ovary syndrome (PCOS) is the most common endocrine
associated with insulin resistance, even in the absence of overweight. The global lipid …

[HTML][HTML] Assisted reproductive technology outcomes and gene expression in unexplained infertility patients

B Vaigauskaitė-Mažeikienė, R Baušytė… - Frontiers in cell and …, 2023 - frontiersin.org
Background: Unexplained infertility (UI) can be a frustrating and challenging diagnosis for
doctors and couples as it can be difficult to understand why they are unable to conceive …

Inflammation and conception in a prospective time-to-pregnancy cohort

AMZ Jukic, CR Weinberg, SL Mumford, AZ Steiner - Epidemiology, 2022 - journals.lww.com
Background: Inflammation may contribute to subfertility but this has not been well-explored
in large prospective cohort studies. Methods: We conducted a prospective 12-month cohort …