Brugada syndrome (BrS) is a rare hereditary arrhythmia disorder, with a distinctive ECG
pattern, correlated with an increased risk of ventricular arrhythmias and sudden cardiac …

Brugada syndrome (BrS) is diagnosed by a coved-type ST-segment elevation in the right
precordial leads on the electrocardiogram (ECG), and it is associated with an increased risk …

Summary Background Brugada syndrome (BrS) is a cardiac channelopathy that can result in
sudden cardiac death (SCD). SCN5A is the most frequent gene linked to BrS, but the …

The right ventricular outflow tract (RVOT) is the major origin of ventricular arrhythmias,
including premature ventricular contractions, idiopathic ventricular arrhythmias, Brugada …

Brugada syndrome (BrS) is a hereditary disorder, characterized by a specific
electrocardiogram pattern and highly related to an increased risk of sudden cardiac death …

The evolution of the current dogma surrounding Brugada syndrome (BrS) has led to a
significant debate about the real usefulness of genetic testing in this syndrome. Since BrS is …

Sudden cardiac death results from arrhythmias commonly caused by channelopathies and
cardiomyopathies, often due to several genetic factors. An emerging concept is that these …

Sudden cardiac death due to malignant ventricular arrhythmias remains the major cause of
mortality in the postindustrial world. Defective intracellular Ca 2+ homeostasis has been well …

In Brugada syndrome, even within the same family where all affected individuals share the
same mutation, phenotypic variation is prominent, with variable penetrance and expressivity …

Ajmaline is an anti-arrhythmic drug that is used to unmask the type-1 Brugada syndrome
(BrS) electrocardiogram pattern to diagnose the syndrome. Thus, the disease is defined at …