Human milk lipids provide the infant with energy and essential vitamins, polyunsaturated
fatty acids, and bioactive components. Adding complex lipids and milk fat globule …

Cholesterol is an important lipid molecule in cell membranes and lipoproteins. Cholesterol is
also a precursors of steroid hormones, bile acids, and vitamin D. Abnormal levels of …

Polar lipids including glycerophospholipids and sphingophospholipids are important
nutrients and milk is a major source, particularly for infants. This systematic review describes …

Background: Statins represent a class of medications widely prescribed to efficiently treat
dyslipidemia. These drugs inhibit 3-βhydroxy 3β-methylglutaryl Coenzyme A reductase …

Cholesterol is a key component of the cell membrane that impacts the permeability, fluidity,
and functions of membrane-bound proteins. It also participates in synaptogenesis, synaptic …

Parkinson's disease (PD) is a neurodegenerative disease characterized by deposition of α-
synuclein and aggregation of Lewy bodies. Cholesterol is involved with PD neuropathology …

Statins are commonly prescribed medications widely investigated for their potential actions
on the brain and mental health. Pre-clinical and clinical evidence suggests that statins may …

Cholesterol is essential for neuronal activity and function. Cholesterol depletion in the
plasma membrane impairs synaptic transmission. However, the molecular mechanisms by …

Statins are some of the most widely used drugs worldwide, but one of their major side effects
is myotoxicity. Using mouse myoblast (C2C12) and human alveolar rhabdomyosarcoma cell …

The mevalonate (MVA)/cholesterol pathway is crucial for central nervous system (CNS)
development and function and consequently, any dysfunction of this fundamental metabolic …