Physiologically based pharmacokinetic modelling of drugs in pregnancy: a mini‐review on availability and limitations
M Berezowska, P Sharma… - Fundamental & …, 2024 - Wiley Online Library
Physiologically based pharmacokinetic (PBPK) modelling in pregnancy is a relatively new
approach that is increasingly being used to assess drug systemic exposure in pregnant …
approach that is increasingly being used to assess drug systemic exposure in pregnant …
Physiologically based pharmacokinetic model for older adults and its application in geriatric drug research
X Wu, JEV Sia, M Hai, X Lai, H Li… - Current Drug …, 2023 - ingentaconnect.com
Drug-related adverse events are higher in older patients than in non-older patients,
increasing the risk of medication and reducing compliance. Aging is accompanied by a …
increasing the risk of medication and reducing compliance. Aging is accompanied by a …
Evaluating Drug Interactions between Ritonavir and Opioid Analgesics: Implications from Physiologically Based Pharmacokinetic Simulation
L Ni, Z Cao, J Jiang, W Zhang, W Hu, Q Zhang… - Pharmaceuticals, 2024 - mdpi.com
Several commonly used opioid analgesics, such as fentanyl, sufentanil, alfentanil, and
hydrocodone, are by report primarily metabolized by the CYP3A4 enzyme. The concurrent …
hydrocodone, are by report primarily metabolized by the CYP3A4 enzyme. The concurrent …
The In Vitro, In Vivo, and PBPK Evaluation of a Novel Lung-Targeted Cardiac-Safe Hydroxychloroquine Inhalation Aerogel
Hydroxychloroquine (HCQ) was repurposed for COVID-19 treatment. Subtherapeutic HCQ
lung levels and cardiac toxicity of oral HCQ were overcome by intratracheal (IT) …
lung levels and cardiac toxicity of oral HCQ were overcome by intratracheal (IT) …
News in DMPT: leaders in pharmacogenetics section
I Fricke-Galindo, A LLerena - Drug Metabolism and Personalized …, 2023 - degruyter.com
Drug Metabolism and Personalized Therapy (DMPT) is the official journal of the European
Society of Pharmacogenomics and Personalised Therapy (ESPT)[1], and it also collaborates …
Society of Pharmacogenomics and Personalised Therapy (ESPT)[1], and it also collaborates …