Ventricular septal defect

DJ Penny, GW Vick - The Lancet, 2011 - thelancet.com
Ventricular septal defects account for up to 40% of all congenital cardiac malformations. The
diagnosis encompasses a broad range of anomalies, including isolated defects and those …

NKX2–5: an update on this hypermutable homeodomain protein and its role in human congenital heart disease (CHD)

SM Reamon‐Buettner, J Borlak - Human mutation, 2010 - Wiley Online Library
Congenital heart disease (CHD) is among the most prevalent and fatal of all birth defects.
Deciphering its causes, however, is complicated, as many patients affected by CHD have no …

[PDF][PDF] Factors affecting the quality of life in children with congenital heart disease

D Nousi, A Christou - Health Science Journal, 2010 - researchgate.net
Congenital heart diseases are the second leading cause of death in infancy and childhood,
as well as the only cause of heart disease in the pediatric population in the developing …

Epigenetics and congenital heart diseases

L Linglart, D Bonnet - Journal of Cardiovascular Development and …, 2022 - mdpi.com
Congenital heart disease (CHD) is a frequent occurrence, with a prevalence rate of almost
1% in the general population. However, the pathophysiology of the anomalous heart …

Genetic Alterations of Transcription Factors and Signaling Molecules Involved in the Development of Congenital Heart Defects—A Narrative Review

AC Bolunduț, C Lazea, CM Mihu - Children, 2023 - mdpi.com
Congenital heart defects (CHD) are the most common congenital abnormality, with an
overall global birth prevalence of 9.41 per 1000 live births. The etiology of CHDs is complex …

Overexpression of FABP3 promotes apoptosis through inducing mitochondrial impairment in embryonic cancer cells

GX Song, YH Shen, YQ Liu, W Sun… - Journal of cellular …, 2012 - Wiley Online Library
Fatty acid‐binding protein 3 (FABP3) is a low‐molecular‐weight protein with a distinct tissue
distribution that may play an important role in fatty acid transport, cell growth, cellular …

Health-related quality of life in children with congenital heart disease following interventional closure versus minimally invasive closure

Y Yuan, B Pan, X Liang, T Lv, J Tian - Frontiers in Cardiovascular …, 2022 - frontiersin.org
Introduction The presence of atrial septal defect (ASD) or ventricular septal defect (VSD)
significantly affects children's quality of life and, if not treated adequately, can contribute to …

Tissue engineering: Relevance to neonatal congenital heart disease

KM Blum, GJM Mirhaidari, CK Breuer - Seminars in Fetal and Neonatal …, 2022 - Elsevier
Congenital heart disease (CHD) represents a large clinical burden, representing the most
common cause of birth defect-related death in the newborn. The mainstay of treatment for …

Cambiando el paradigma en las cardiopatías congénitas: de la anatomía a la etiología molecular

IE Monroy-Muñoz, N Pérez-Hernández… - Gaceta Médica de …, 2013 - medigraphic.com
El desarrollo embrionario del corazón consiste en una serie de interacciones
morfogenéticas complejas y específicas, que requieren del correcto funcionamiento de cada …

[HTML][HTML] The effects of reduced hemodynamic loading on morphogenesis of the mouse embryonic heart

TG Hoog, SJ Fredrickson, CW Hsu, SM Senger… - Developmental …, 2018 - Elsevier
Abstract Development of the embryonic heart involves an intricate network of biochemical
and genetic cues to ensure its proper growth and morphogenesis. However, studies from …