The maintenance of iron homeostasis is essential for proper cardiac function. A growing
body of evidence suggests that iron imbalance is the common denominator in many …

Ferroptosis is an iron-dependent form of regulated cell death with distinct characteristics,
including altered iron homeostasis, reduced defense against oxidative stress, and abnormal …

Targeting ferroptosis, a unique cell death modality triggered by unrestricted lipid
peroxidation, in cancer therapy is hindered by our incomplete understanding of ferroptosis …

Ferroptosis is an iron-dependent, non-apoptotic form of regulated cell death caused by lipid
peroxidation, which is controlled by integrated oxidation and antioxidant systems. The iron …

Abstract Development of resistance to chemotherapy in cancer continues to be a major
challenge in cancer management. Ferroptosis, a unique type of cell death, is mechanistically …

The activation of ferroptosis is a new effective way to treat drug-resistant solid tumors.
Ferroptosis is an iron-mediated form of cell death caused by the accumulation of lipid …

Ferroptosis, an iron-dependent form of regulated cell death driven by peroxidative damages
of polyunsaturated-fatty-acid-containing phospholipids in cellular membranes, has recently …

Ferroptosis is an iron-dependent regulated necrosis mediated by lipid peroxidation. Cancer
cells survive under metabolic stress conditions by altering lipid metabolism, which may alter …

Ferroptosis is a type of cell death that was described less than a decade ago. It is caused by
the excess of free intracellular iron that leads to lipid (hydro) peroxidation. Iron is essential …

The glutathione (GSH) system is considered to be one of the most powerful endogenous
antioxidant systems in the cardiovascular system due to its key contribution to detoxifying …