Polymeric delivery of therapeutic nucleic acids
R Kumar, CF Santa Chalarca, MR Bockman… - Chemical …, 2021 - ACS Publications
The advent of genome editing has transformed the therapeutic landscape for several
debilitating diseases, and the clinical outlook for gene therapeutics has never been more …
debilitating diseases, and the clinical outlook for gene therapeutics has never been more …
Next‐generation vaccines: nanoparticle‐mediated DNA and mRNA delivery
Nucleic acid vaccines are a method of immunization aiming to elicit immune responses akin
to live attenuated vaccines. In this method, DNA or messenger RNA (mRNA) sequences are …
to live attenuated vaccines. In this method, DNA or messenger RNA (mRNA) sequences are …
Poly(l‐Histidine)‐Mediated On‐Demand Therapeutic Delivery of Roughened Ceria Nanocages for Treatment of Chemical Eye Injury
Abstract Development of topical bioactive formulations capable of overcoming the low
bioavailability of conventional eye drops is critically important for efficient management of …
bioavailability of conventional eye drops is critically important for efficient management of …
[HTML][HTML] Engineering nanoparticle toolkits for mRNA delivery
The concept of using mRNA to produce its own medicine in situ in the body makes it an ideal
drug candidate, holding great potential to revolutionize the way we approach medicine. The …
drug candidate, holding great potential to revolutionize the way we approach medicine. The …
Dendritic mesoporous nanoparticles: structure, synthesis and properties
Recently, dendritic mesoporous silica nanoparticles with widespread applications have
attracted great interest. Despite many publications (> 800), the terminology “dendritic” is …
attracted great interest. Despite many publications (> 800), the terminology “dendritic” is …
Defect‐rich adhesive nanozymes as efficient antibiotics for enhanced bacterial inhibition
Nanozymes have emerged as a new generation of antibiotics with exciting broad‐spectrum
antimicrobial properties and negligible biotoxicities. However, their antibacterial efficacies …
antimicrobial properties and negligible biotoxicities. However, their antibacterial efficacies …
Versatile types of organic/inorganic nanohybrids: from strategic design to biomedical applications
N Zhao, L Yan, X Zhao, X Chen, A Li, D Zheng… - Chemical …, 2018 - ACS Publications
Organic/inorganic nanohybrids have attracted widespread interests due to their favorable
properties and promising applications in biomedical areas. Great efforts have been made to …
properties and promising applications in biomedical areas. Great efforts have been made to …
Silica-based nanoparticles for biomedical applications: from nanocarriers to biomodulators
Conspectus Silica-based nanoparticles (SNPs) are a classic type of material employed in
biomedical applications because of their excellent biocompatibility and tailorable …
biomedical applications because of their excellent biocompatibility and tailorable …
The progress and promise of RNA medicine─ an arsenal of targeted treatments
In the past decade, there has been a shift in research, clinical development, and commercial
activity to exploit the many physiological roles of RNA for use in medicine. With the rapid …
activity to exploit the many physiological roles of RNA for use in medicine. With the rapid …
Bioinspired nanotopographical design of drug delivery systems
JA Finbloom, C Huynh, X Huang… - Nature Reviews …, 2023 - nature.com
Effective drug delivery is important in the treatment of various biomedical conditions, ranging
from autoimmune disorders to cancer and bacterial infections. Nanostructured systems can …
from autoimmune disorders to cancer and bacterial infections. Nanostructured systems can …