[HTML][HTML] Papillary thyroid cancer: genetic alterations and molecular biomarker investigations

MI Abdullah, SM Junit, KL Ng… - … journal of medical …, 2019 - ncbi.nlm.nih.gov
Papillary thyroid cancer (PTC) is the most prevalent form of malignancy among all cancers of
the thyroid. It is also one of the few cancers with a rapidly increasing incidence. PTC is …

Targeting the pentose phosphate pathway increases reactive oxygen species and induces apoptosis in thyroid cancer cells

CL Liu, YC Hsu, JJ Lee, MJ Chen, CH Lin… - Molecular and cellular …, 2020 - Elsevier
The pentose phosphate pathway (PPP) plays an important role in the biosynthesis of
ribonucleotide precursor and NADPH. Cancer cells frequently increase the flux of glucose …

SOX4 is a pivotal regulator of tumorigenesis in differentiated thyroid cancer

CY Kuo, YC Hsu, CL Liu, YS Li, SC Chang… - Molecular and Cellular …, 2023 - Elsevier
The SOX family consists of about 20 transcription factors involved in embryonic
development, reprogramming, and cell fate determination. In this study, we demonstrated …

Upregulation of dendrocyte-expressed seven transmembrane protein is associated with unfavorable outcomes in differentiated thyroid cancer

JJ Lee, YC Hsu, WC Huang, SP Cheng - Endocrine, 2023 - Springer
Purpose Dendritic cell infiltrates are increased in thyroid cancer but may have a defective
ability to provoke effective immune responses. In this study, we aimed to identify potential …

[HTML][HTML] Unraveling the role of the mitochondrial one-carbon pathway in undifferentiated thyroid cancer by multi-omics analyses

SE Lee, S Park, S Yi, NR Choi, MA Lim… - Nature …, 2024 - nature.com
The role of the serine/glycine metabolic pathway (SGP) has recently been demonstrated in
tumors; however, the pathological relevance of the SGP in thyroid cancer remains …

[HTML][HTML] Heme oxygenase-1 inhibitors induce cell cycle arrest and suppress tumor growth in thyroid cancer cells

PS Yang, YC Hsu, JJ Lee, MJ Chen, SY Huang… - International Journal of …, 2018 - mdpi.com
Heme oxygenase-1 (HO-1) is induced by a variety of stimuli and plays a multifaceted role in
cellular protection. We have shown that HO-1 is overexpressed in thyroid cancer and is …

[HTML][HTML] Semaphorin 6A attenuates the migration capability of lung cancer cells via the NRF2/HMOX1 axis

LH Chen, CY Liao, LC Lai, MH Tsai, EY Chuang - Scientific reports, 2019 - nature.com
Cell migration is a fundamental feature of cancer recurrence. Since recurrence is correlated
with high mortality in lung cancer, it follows that reducing cell migration would decrease …

[HTML][HTML] Identification of key pathways and genes in anaplastic thyroid carcinoma via integrated bioinformatics analysis

S Hu, Y Liao, L Chen - … medical journal of experimental and clinical …, 2018 - ncbi.nlm.nih.gov
Identification of Key Pathways and Genes in Anaplastic Thyroid Carcinoma via Integrated
Bioinformatics Analysis - PMC Back to Top Skip to main content NIH NLM Logo Access keys …

[HTML][HTML] PGC1α downregulation and glycolytic phenotype in thyroid cancer

CL Liu, PS Yang, TY Wang, SY Huang, YH Kuo… - Journal of …, 2019 - ncbi.nlm.nih.gov
Increased aerobic glycolysis portends an unfavorable prognosis in thyroid cancer. The
metabolic reprogramming likely results from altered mitochondrial activity and may promote …

miR-200b/c-RAP1B axis represses tumorigenesis and malignant progression of papillary thyroid carcinoma through inhibiting the NF-κB/Twist1 pathway

B Zhou, J Xu, Y Chen, S Gao, X Feng, X Lu - Experimental cell research, 2020 - Elsevier
Papillary thyroid carcinoma (PTC) is a common endocrine malignancy with an increasing
occurrence and recurrence. MicroRNAs (miRNAs) have been widely acknowledged to be …