Ketamine for the treatment of major depression: a systematic review and meta-analysis
Background Intranasal esketamine has received regulatory approvals for the treatment of
depression. Recently a large trial of repeated dose racemic ketamine also demonstrated …
depression. Recently a large trial of repeated dose racemic ketamine also demonstrated …
Number needed to treat (NNT) for ketamine and esketamine in adults with treatment-resistant depression: A systematic review and meta-analysis
ATH Kwan, KM Teopiz, S Wong, JD Rosenblat… - Journal of Affective …, 2024 - Elsevier
Background Ketamine has been established as efficacious in adults living with Treatment-
resistant Depression (TRD). Toward providing a quantifiable estimate of the clinical …
resistant Depression (TRD). Toward providing a quantifiable estimate of the clinical …
[HTML][HTML] Change in negative affective bias following a single ketamine treatment for treatment-resistant depression
AJ Harvey, S Nikolin, N Chand, W Flanney… - Depression and …, 2023 - hindawi.com
Ketamine has recently emerged as a highly effective new treatment for people with treatment-
resistant depression with rapid antidepressant effects. However, these effects are often short …
resistant depression with rapid antidepressant effects. However, these effects are often short …
Oral esketamine in patients with treatment-resistant depression: a double-blind, randomized, placebo-controlled trial with open-label extension
SY Smith-Apeldoorn, JKE Veraart, J Kamphuis… - Molecular …, 2024 - nature.com
About one-third of patients with depression do not achieve adequate response to current
treatment options. Although intravenous and intranasal administrations of (es) ketamine …
treatment options. Although intravenous and intranasal administrations of (es) ketamine …
Multidisciplinary development of guidelines for ketamine treatment for treatment-resistant major depression disorder for use by adult specialist mental health services …
BackgroundThe evidence base for racemic ketamine treatment for treatment-resistant major
depressive disorder (TRD) continues to expand, but there are major challenges translating …
depressive disorder (TRD) continues to expand, but there are major challenges translating …
Use of ketamine for treatment resistant depression: updated review of literature and practical applications to a community ketamine program in Edmonton, Alberta …
C Chrenek, B Duong, A Khullar, C McRee… - Frontiers in …, 2024 - frontiersin.org
Background Though intravenous (IV) ketamine and intranasal (IN) esketamine are noted to
be efficacious for treatment-resistant depression (TRD), access to each of these treatments …
be efficacious for treatment-resistant depression (TRD), access to each of these treatments …
[HTML][HTML] Cognitive outcomes from the randomised, active-controlled Ketamine for Adult Depression Study (KADS)
Background Due to its rapid antidepressant effect, ketamine has recently been clinically
translated for people with treatment-resistant depression. However, its cognitive profile …
translated for people with treatment-resistant depression. However, its cognitive profile …
Ketamine for treatment-resistant major depressive disorder: Double-blind active-controlled crossover study
P Glue, S Neehoff, B Beaglehole… - Journal of …, 2024 - journals.sagepub.com
Background: The N-methyl-D-aspartate antagonist ketamine has rapid onset antidepressant
activity in treatment-resistant depression (TRD). Aims: To evaluate mood rating, safety and …
activity in treatment-resistant depression (TRD). Aims: To evaluate mood rating, safety and …
Synergistic use of deep TMS therapy with IV ketamine infusions for major depressive disorder: a pilot study
NA Shanok, S Muzac, L Brown, M Barrera… - …, 2024 - Springer
Abstract Objective Major Depressive Disorder (MDD) is a pervasive psychiatric condition
effecting approximately 21 million adults in the US (8.4%). An estimated 30–60% of patients …
effecting approximately 21 million adults in the US (8.4%). An estimated 30–60% of patients …
The Study of Ketamine for Youth Depression (SKY-D): study protocol for a randomised controlled trial of low-dose ketamine for young people with major depressive …
Background Existing treatments for young people with severe depression have limited
effectiveness. The aim of the Study of Ketamine for Youth Depression (SKY-D) trial is to …
effectiveness. The aim of the Study of Ketamine for Youth Depression (SKY-D) trial is to …