Biomaterials and bioactive natural products from marine invertebrates: From basic research to innovative applications

G Romano, M Almeida, A Varela Coelho, A Cutignano… - Marine Drugs, 2022 - mdpi.com
Aquatic invertebrates are a major source of biomaterials and bioactive natural products that
can find applications as pharmaceutics, nutraceutics, cosmetics, antibiotics, antifouling …

Mining natural products for advanced biofuels and sustainable bioproducts

X Li, AE Gadar-Lopez, L Chen, S Jayachandran… - Current Opinion in …, 2023 - Elsevier
Highlights•Natural products offer a broad chemical catalog for bio-based product
development.•Genome mining tools for identifying BGCs.•Isoprenoid, nonribosomal peptide …

Systematic mining of the human microbiome identifies antimicrobial peptides with diverse activity spectra

AM King, Z Zhang, E Glassey, P Siuti, J Clardy… - Nature …, 2023 - nature.com
Human-associated bacteria secrete modified peptides to control host physiology and
remodel the microbiota species composition. Here we scanned 2,229 Human Microbiome …

[图书][B] Natural product biosynthesis

CT Walsh, Y Tang - 2017 - books.google.com
Authored by leading experts in the enzymology of natural product biosynthesis, this textbook
provides a thorough description of the types of natural products, the biosynthetic pathways …

Penicillium chrysogenum, a Vintage Model with a Cutting-Edge Profile in Biotechnology

F Fierro, I Vaca, NI Castillo, RO García-Rico, R Chávez - Microorganisms, 2022 - mdpi.com
The discovery of penicillin entailed a decisive breakthrough in medicine. No other medical
advance has ever had the same impact in the clinical practise. The fungus Penicillium …

Ecological niche-inspired genome mining leads to the discovery of crop-protecting nonribosomal lipopeptides featuring a transient amino acid building block

S Götze, R Vij, K Burow, N Thome… - Journal of the …, 2023 - ACS Publications
Investigating the ecological context of microbial predator–prey interactions enables the
identification of microorganisms, which produce multiple secondary metabolites to evade …

Evaluation and Genome Analysis of Bacillus subtilis YB-04 as a Potential Biocontrol Agent Against Fusarium Wilt and Growth Promotion Agent of Cucumber

W Xu, Q Yang, F Yang, X Xie, PH Goodwin… - Frontiers in …, 2022 - frontiersin.org
Cucumber wilt caused by Fusarium oxysporum f. sp. cucumerinum (Foc) is a highly
destructive disease that leads to reduced yield in cucumbers. In this study, strain YB-04 was …

[HTML][HTML] Pederins, mycalamides, onnamides and theopederins: Distinctive polyketide families with intriguing therapeutic potentialities

MA Tammam, A El-Demerdash - Current Research in Biotechnology, 2023 - Elsevier
In this comprehensive review article, an in-depth exploration over the period from 1949 to
2023 is presented, focusing on the discovery, chemistry, biosynthesis and therapeutic …

Type II Polyketide Synthases: A Bioinformatics‐Driven Approach

S Xie, L Zhang - ChemBioChem, 2023 - Wiley Online Library
Bioinformatics has become an indispensable tool for natural products research in the
genomic era. One of the key challenges is to accurately convert sequence data of a …

Antimicrobial and anti-inflammatory cyclic tetrapeptides from the co-cultures of two marine-derived fungi

Q Li, S Li, S Li, X Hao, A Wang, S Si, Y Xu… - Journal of Natural …, 2024 - ACS Publications
Violaceotides B–E (1–4), four new cyclic tetrapeptides, along with seven known compounds,
were identified from the sponge-associated Aspergillus insulicola IMB18-072 co-cultivated …