Kidney stone disease is a crystal concretion formed usually within the kidneys. It is an
increasing urological disorder of human health, affecting about 12% of the world population …

Background Urolithiasis has been a major health concern for centuries, primarily owing to
the limited treatment options in the physician's armamentarium. However, various studies …

Calcium nephrolithiasis is the most common form of renal stone disease, with calcium
oxalate (CaOx) being the predominant constituent of renal stones. Current in vitro evidence …

Retention of crystals in the kidney is an essential early step in renal stone formation. Studies
with renal tubular cells in culture indicate that hyaluronan (HA) and osteopontin (OPN) and …

Urinary stone disease has afflicted humankind since antiquity. A bladder stone was found in
an Egyptian skeleton more than 7000 years old. 8 Urolithiasis is a common disorder …

In the indigenous system of medicine in India, the plant Sesbania grandiflora is claimed to
be useful for various ailments, and one such use is for the treatment of renal calculi. The …

OBJECTIVE To determine whether vitamin E prevents hyperoxaluria‐induced stone
formation, using a new animal model of calcium oxalate stone disease, as our previous in …

Nephrolithiasis requires formation of crystals followed by their retention and accumulation in
the kidney. Crystal retention can be caused by the association of crystals with the epithelial …

Purpose: We evaluated whether epigallocatechin gallate (EGCG), a main constituent of
green tea polyphenols, could protect against cellular toxicity by oxalate and whether green …

Studies in various tissues, including the kidney, have demonstrated that toxins elicit
apoptosis under certain conditions and necrosis under others. The nature of the response …