What is the relationship between exercise and metabolic abnormalities? A review of the metabolic syndrome

S Carroll, M Dudfield - Sports medicine, 2004 - Springer
Prevention of the metabolic syndrome and treatment of its main characteristics are now
considered of utmost importance in order to combat the epidemic of type 2 diabetes mellitus …

Lipid and lipoprotein dysregulation in insulin resistant states

RK Avramoglu, H Basciano, K Adeli - Clinica chimica acta, 2006 - Elsevier
Insulin resistant states are commonly associated with an atherogenic dyslipidemia that
contributes to significantly higher risk of atherosclerosis and cardiovascular disease. Indeed …

Effects of insulin resistance and type 2 diabetes on lipoprotein subclass particle size and concentration determined by nuclear magnetic resonance

WT Garvey, S Kwon, D Zheng, S Shaughnessy… - Diabetes, 2003 - Am Diabetes Assoc
The insulin resistance syndrome (IRS) is associated with dyslipidemia and increased
cardiovascular disease risk. A novel method for detailed analyses of lipoprotein subclass …

[HTML][HTML] Mechanisms of hepatic very low density lipoprotein overproduction in insulin resistance: evidence for enhanced lipoprotein assembly, reduced intracellular …

C Taghibiglou, A Carpentier, SC Van Iderstine… - Journal of Biological …, 2000 - ASBMB
A novel animal model of insulin resistance, the fructose-fed Syrian golden hamster, was
employed to investigate the mechanisms mediating the overproduction of very low density …

Defective regulation of triglyceride metabolism by insulin in the liver in NIDDM

R Malmström, CJ Packard, M Caslake, D Bedford… - Diabetologia, 1997 - Springer
Insulin administration to healthy subjects inhibits the production of very low density
lipoprotein (VLDL) 1 (Svedbergs flotation (Sf) rate 60–400) without affecting that of VLDL2 …

[HTML][HTML] A lipogenic diet in mice with a disruption of the stearoyl-CoA desaturase 1 gene reveals a stringent requirement of endogenous monounsaturated fatty acids …

M Miyazaki, YC Kim, JM Ntambi - Journal of lipid research, 2001 - ASBMB
Stearoyl-CoA desaturase (SCD) catalyzes the de novo biosynthesis of oleate and
palmitoleate, which are the major fatty acids found in triglycerides, cholesteryl esters, and …

[HTML][HTML] Apolipoprotein B metabolism and the distribution of VLDL and LDL subfractions

CJ Packard, T Demant, JP Stewart, D Bedford… - Journal of lipid …, 2000 - ASBMB
Apolipoprotein B (apoB) metabolism was investigated in 20 men with plasma triglyceride
0.66–2.40 mmol/l and plasma cholesterol 3.95–6.95 mmol/l. Kinetics of VLDL 1 (S f 60–400) …

Clustering of dyslipidemia, hyperuricemia, diabetes, and hypertension and its association with fasting insulin and central and overall obesity in a general population

MI Schmidt, RL Watson, BB Duncan, P Metcalf… - Metabolism, 1996 - Elsevier
Clustering of elevated triglycerides, decreased high-density lipoprotein cholesterol (HDL-C),
hyperuricemia, diabetes, and hypertension has been related to insulin resistance/high …

[HTML][HTML] Hepatic very low density lipoprotein-ApoB overproduction is associated with attenuated hepatic insulin signaling and overexpression of protein-tyrosine …

C Taghibiglou, F Rashid-Kolvear… - Journal of Biological …, 2002 - ASBMB
A fructose-fed hamster model of insulin resistance was previously documented to exhibit
marked hepatic very low density lipoprotein (VLDL) overproduction. Here, we investigated …

Adverse endothelial function and the insulin resistance syndrome

JE Tooke, MM Hannemann - Journal of internal medicine, 2000 - Wiley Online Library
Tooke JE, Hannemann MM (School of Postgraduate Medicine and Vascular Health
Sciences, University of Exeter, Devon). Adverse endothelial function and the insulin …