Patients with chronic kidney disease (CKD) exhibit an elevated cardiovascular risk
manifesting as coronary artery disease, heart failure, arrhythmias, and sudden cardiac …

Circular RNAs (circRNAs) are a class of endogenously expressed regulatory RNAs with a
single-stranded circular structure. They are generated by back splicing and their expression …

Cardiovascular disease (CVD) is a major cause of death in patients with chronic kidney
disease (CKD). Both conditions are rising in incidence as well as prevalence, creating poor …

Chronic kidney disease (CKD) is associated with the development of mineral bone disorder
(MBD), osteoporosis, and fragility fractures. Among CKD patients, adynamic bone disease or …

Vascular calcification (VC) is highly prevalent in aging, diabetes mellitus, and chronic kidney
disease (CKD). VC is a strong predictor of cardiovascular morbidity and mortality in the CKD …

The endothelium is considered to be the gatekeeper of the vessel wall, maintaining and
regulating vascular integrity. In patients with chronic kidney disease, protective endothelial …

Inorganic phosphate (Pi) plays a critical function in many tissues of the body: for example, as
part of the hydroxyapatite in the skeleton and as a substrate for ATP synthesis. Pi is the main …

The heart and the vascular tree undergo major structural and functional changes when
kidney function declines and renal replacement therapy is required. The many …

Objectives To investigate the effects of personal calcium supplement use on cardiovascular
risk in the Women's Health Initiative Calcium/Vitamin D Supplementation Study (WHI CaD …

Results Median parathyroid hormone increased from phase 1 to phase 4 in all regions
except for Japan, where it remained stable. Prescriptions of intravenous vitamin D analogs …