Mesenchymal condensation in tooth development and regeneration: a focus on translational aspects of organogenesis

BD Sui, CX Zheng, WM Zhao, K Xuan… - Physiological …, 2023 - journals.physiology.org
The teeth are vertebrate-specific, highly specialized organs performing fundamental
functions of mastication and speech, the maintenance of which is crucial for orofacial …

Melatonin enhances osteogenic differentiation of dental pulp mesenchymal stem cells by regulating MAPK pathways and promotes the efficiency of bone regeneration …

YH Chan, KN Ho, YC Lee, MJ Chou, WZ Lew… - Stem Cell Research & …, 2022 - Springer
Background Mesenchymal stem cell (MSC)-based tissue engineering plays a major role in
regenerative medicine. However, the efficiency of MSC transplantation and survival of …

Regulation mechanisms and maintenance strategies of stemness in mesenchymal stem cells

N Jiang, X Tian, Q Wang, J Hao, J Jiang… - Stem cell reviews and …, 2024 - Springer
Stemness pertains to the intrinsic ability of mesenchymal stem cells (MSCs) to undergo self-
renewal and differentiate into multiple lineages, while simultaneously impeding their …

3D hESC exosomes enriched with miR-6766-3p ameliorates liver fibrosis by attenuating activated stellate cells through targeting the TGFβRII-SMADS pathway

N Wang, X Li, Z Zhong, Y Qiu, S Liu, H Wu… - Journal of …, 2021 - Springer
Background Exosomes secreted from stem cells exerted salutary effects on the fibrotic liver.
Herein, the roles of exosomes derived from human embryonic stem cell (hESC) in anti …

Effect of different bone grafting materials and mesenchymal stem cells on bone regeneration: A micro-computed tomography and histomorphometric study in a rabbit …

ST Shiu, WF Lee, SM Chen, LT Hao, YT Hung… - International journal of …, 2021 - mdpi.com
This study evaluated the new bone formation potential of micro–macro biphasic calcium
phosphate (MBCP) and Bio-Oss grafting materials with and without dental pulp-derived …

Evaluating the defect targeting effects and osteogenesis promoting capacity of exosomes from 2D-and 3D-cultured human adipose-derived stem cells

R Chen, T Feng, S Cheng, M Chen, Y Li, Z Yu, Z Xu… - Nano Today, 2023 - Elsevier
Exosomes derived from stem cells show great therapeutic potential in bone defect repair.
Systemic administration of exosomes represents as a minimally invasive delivery approach; …

Wnt3a‐Loaded Hydroxyapatite Nanowire@ Mesoporous Silica Core− Shell Nanocomposite Promotes the Regeneration of Dentin− Pulp Complex via Angiogenesis …

N Luo, YW Deng, J Wen, XC Xu… - Advanced …, 2023 - Wiley Online Library
Pulp exposure often leads to pulp necrosis, root fractures, and ultimate tooth loss. The repair
of the exposure site with pulp capping treatment is of great significance to preserving pulp …

Interactions of neuronally induced stem cells from apical papilla spheres, stems cells from apical papilla, and human umbilical vascular endothelial cells on …

MS Basabrain, J Zhong, J Liu, Y Zhang… - Journal of …, 2024 - Elsevier
Introduction Stem cell–based dental pulp regeneration has been extensively studied, mainly
focusing on exploiting dental stem cells' osteogenic and angiogenic potentials. Dental stem …

Association of mesenchymal stem cells derived from bone marrow and adipose tissue enhances bone repair in rat calvarial defects

GG Campos Totoli, RL Bighetti-Trevisan… - Regenerative …, 2023 - Taylor & Francis
Aim: We evaluated the bone repair induced by MSCs from adipose tissue (AT-MSCs) and
bone marrow (BM-MSCs) injected into rat calvarial defects at two time points. Methods & …

Human dental pulp stem cell monolayer and spheroid therapy after spinal motor root avulsion in adult rats

SM Paes, MV de Castro, RM Barbosa, LP Cartarozzi… - Brain Research, 2023 - Elsevier
Spinal cord injuries result in severe neurological deficits and neuronal loss, with poor
functional recovery. Mesenchymal stem cells have shown promising results; therefore the …