[HTML][HTML] A lifecourse mendelian randomization study highlights the long-term influence of childhood body size on later life heart structure
K O'Nunain, C Park, H Urquijo, GM Leyden… - PLoS …, 2022 - journals.plos.org
Children with obesity typically have larger left ventricular heart dimensions during
adulthood. However, whether this is due to a persistent effect of adiposity extending into …
adulthood. However, whether this is due to a persistent effect of adiposity extending into …
[HTML][HTML] Lifestyle choices mediate the association between educational attainment and BMI in older adults in China: A cross-sectional study
L Wang, J Ren, J Chen, R Gao, B Bai, H An… - Frontiers in public …, 2022 - frontiersin.org
As the Chinese population ages, unhealthfully high body mass index (BMI) levels in older
adults are becoming a public health concern as an unhealthfully high BMI is an ill-being …
adults are becoming a public health concern as an unhealthfully high BMI is an ill-being …
[HTML][HTML] Utility of polygenic scores across diverse diseases in a hospital cohort for predictive modeling
Polygenic scores estimate genetic susceptibility to diseases. We systematically calculated
polygenic scores across 457 phenotypes using genotyping array data from China Medical …
polygenic scores across 457 phenotypes using genotyping array data from China Medical …
[HTML][HTML] Decoding Genetics, Ancestry, and Geospatial Context for Precision Health
Abstract Mass General Brigham, an integrated healthcare system based in the Greater
Boston area of Massachusetts, annually serves 1.5 million patients. We established the …
Boston area of Massachusetts, annually serves 1.5 million patients. We established the …
[HTML][HTML] Trends in the ability of socioeconomic position to predict individual body mass index: an analysis of repeated cross-sectional data, 1991–2019
Background The widening of group-level socioeconomic differences in body mass index
(BMI) has received considerable research attention. However, the predictive power of …
(BMI) has received considerable research attention. However, the predictive power of …
[HTML][HTML] Socio-economic differences in body mass index: the contribution of genetic factors
K Silventoinen, H Lahtinen, F Kilpi, TT Morris… - International Journal of …, 2024 - nature.com
Background Higher mean body mass index (BMI) among lower socioeconomic position
(SEP) groups is well established in Western societies, but the influence of genetic factors on …
(SEP) groups is well established in Western societies, but the influence of genetic factors on …
Trans‐ethnic polygenic risk scores for body mass index: An international hundred K+ cohorts consortium study
Background While polygenic risk scores hold significant promise in estimating an
individual's risk of developing a complex trait such as obesity, their application in the clinic …
individual's risk of developing a complex trait such as obesity, their application in the clinic …
Genetically Predicted Blood Pressure and Cognition in Midlife: A UK Biobank Study
BACKGROUND: This UK Biobank study uses a mendelian randomization approach to
mitigate the variability and confounding that has affected previous analyses of the …
mitigate the variability and confounding that has affected previous analyses of the …
Trends across time in socioeconomic differences in body mass index: a comparison of population and individual-level approaches
Background Socioeconomic differences in body mass index (BMI) have widened alongside
the obesity epidemic. However, the utility of socioeconomic position (SEP) indicators at the …
the obesity epidemic. However, the utility of socioeconomic position (SEP) indicators at the …
[HTML][HTML] Gene-environment Interplay in the Development of Overweight
M de Roo, C Hartman, R Veenstra, IM Nolte… - Journal of Adolescent …, 2023 - Elsevier
Purpose Overweight in youth is influenced by genes and environment. Gene-environment
interaction (G× E) has been demonstrated in twin studies and recent developments in …
interaction (G× E) has been demonstrated in twin studies and recent developments in …