There is growing evidence that chronic kidney disease (CKD) is an independent risk factor
for cognitive impairment, especially due to vascular damage, blood–brain barrier disruption …

Opioids are widely used in chronic pain management, despite major concerns about their
risk of adverse events, particularly abuse, misuse, and respiratory depression from …

Even prior to the COVID-19 pandemic, rates of ambulatory surgeries and ambulatory
patients presenting with substance use disorder were increasing, and the end of lockdown …

Opioids are widely used in cancer and non-cancer pain management. However, many
transporters at the blood–brain barrier (BBB), such as P-glycoprotein (P-gp, ABCB1/MDR1) …

Simple Summary Leukemia, the most common form of childhood cancer, accounts for about
30 percent of all cancers that affect children and young adults. Although pain is a common …

Zusammenfassung Hintergrund Bei Patienten mit entzündlich rheumatischen Erkrankungen
und Niereninsuffizienz ergeben sich für den Therapeuten zwei Herausforderungen: die …

Recently, the concept of psychonephrology was developed and has been recognized as a
field of study that focuses on nephrology and mental health fields, such as psychiatry and …

BACKGROUND: Patients undergoing dialysis pose therapeutic challenges in terms of
polypharmacy, administration of potentially inappropriate drugs, and drugs with the potential …

Patients with chronic kidney disease (CKD) report high pain levels, but reduced renal
clearance eliminates many analgesic options; therefore, 30–50% of CKD patients have …

Pain associated with severe burn injury is one of the most intense and clinically challenging
to manage, as the metabolic imbalances associated with the inflammation caused by the …