The main goal of a novel drug development is to obtain it with optimal physiochemical,
pharmaceutical and biological properties. Pharmaceutical companies and scientists modify …

Pharmaceutical co-crystals have been explored by many researchers as a strategy to
optimize physicochemical properties of solid-state drugs. Their improvements of solubility …

Pharmaceutical cocrystals are highly interesting due to their effect on physicochemical
properties and their role in separation technologies, particularly for chiral molecules …

Co-crystallization is a promising approach for improving physical and pharmacological
properties of API, viz., solubility, dissolution rate, stability, hygroscopicity, tablet ability …

Mechanical treatment of dry powder mixtures has often been reported to give new
compounds. The assumption of neat mechanochemical conditions must, however, be made …

The present work reports two novel pharmaceutical co-crystals; 2: 1 isoniazid-glutaric acid
(INHGA) and 2: 1 pyrazinamide-glutaric acid (PGA). Isoniazid and pyrazinamide are key first …

A novel multicomponent crystal (MC) of mefenamic acid (MA) and N-methyl-d-glucamine
(MG) had been prepared to improve the physicochemical properties of poorly soluble drugs …

Hot melt extrusion (HME) is emerging as a continuous, single-step, scalable, and industrially
feasible process for the production of cocrystals. HME has gained momentum as a …

Crystal engineering of temporary adhesion is important in diverse fields ranging from
healthcare to manufacturing. Molecular solids—a broad class of crystalline materials …

Quality control (QC) is the most important key issue in the pharmaceutical industry to ensure
the quality of drug products. Many analytical instruments and techniques in pharmaceutical …