Nucleolar stress reflects a misfunction of the nucleolus caused by a failure in ribosome
biogenesis and defective nucleolar architecture. Various causes have been reported, most …

Parkinson's disease (PD) is the most common α-synucleinopathy worldwide. The
pathognomonic hallmark of PD is the misfolding and propagation of the α-synuclein (α-syn) …

In recent years, inhibiting tumor cell activity by triggering cell ferroptosis has become a
research hotspot. The development of generic targeted nanotherapeutics might bring new …

Gastrointestinal cancers are a group of cancers occurred in gastrointestinal tissues with high
morbidity and mortality rate. Although numerous studies were conducted on the …

Colon adenocarcinoma (COAD) is one of the most common clinically malignant tumours of
the digestive system, with high incidence and mortality and poor prognosis. Interferon …

Autophagy plays a critical role in maintaining cellular homeostasis and responding to
various stress conditions by the degradation of intracellular components. In this narrative …

Autophagy is a conserved cytoprotective process, aberrations in which lead to numerous
degenerative disorders. While the cytoplasmic components of autophagy have been …

Ischemic stroke (IS) is a severe disease with a high disability, recurrence, and mortality
rates. Autophagy, a highly conserved process that degrades damaged or aging organelles …

Diabetes-associated periodontitis (DP) presents severe inflammation and resistance to
periodontal conventional treatment, presenting a significant challenge in clinical …

Autophagy, the process that enables the recycling and degradation of cellular components,
is essential for homeostasis, which occurs in response to various types of stress. Autophagy …