Autophagy is an essential, conserved lysosomal degradation pathway that controls the
quality of the cytoplasm by eliminating protein aggregates and damaged organelles. It …

Autophagy, or cellular self-digestion, is a cellular pathway crucial for development,
differentiation, survival, and homeostasis. Its implication in human diseases has been …

Exercise and dietary intervention are currently available strategies to treat nonalcoholic fatty
liver disease (NAFLD), while the underlying mechanism remains controversial. Emerging …

Type II diabetes mellitus and its related complications are growing public health problems.
Many natural products present in our diet, including polyphenols, can be used in treating …

Autophagy is an evolutionarily conserved process that plays a crucial role in maintaining a
series of cellular functions. It has been found that autophagy is closely involved in the …

Insulin resistance (IR), a key component of the metabolic syndrome, precedes the
development of diabetes, cardiovascular disease, and Alzheimer's disease. Its etiological …

With regard to cell biology, one area of focus that has shifted back and forth over the years
has been the relative emphasis on catabolic versus anabolic processes: the breakdown of …

Autophagy deregulation during obesity contributes to the pathogenesis of diverse metabolic
disorders. However, without understanding the molecular mechanism of obesity interference …

Scope Resveratrol (RSV), a natural polyphenol, has been reported to attenuate
nonalcoholic fatty liver disease (NAFLD); however, its underlying mechanism is unclear …

Autophagy is a conserved degradation process crucial to maintaining the primary function of
cellular and organismal metabolism. Impaired autophagy could develop numerous …