Endogenous opiates and behavior: 2022
RJ Bodnar - Peptides, 2023 - Elsevier
This paper is the forty-fifth consecutive installment of the annual anthological review of
research concerning the endogenous opioid system, summarizing articles published during …
research concerning the endogenous opioid system, summarizing articles published during …
Heroin-and fentanyl-induced respiratory depression in a rat plethysmography model: potency, tolerance, and sex differences
RCN Marchette, ER Carlson, EV Frye… - … of Pharmacology and …, 2023 - ASPET
The opioid overdose death toll in the United States is an ongoing public health crisis. We
characterized the magnitude and duration of respiratory depression, the leading cause of …
characterized the magnitude and duration of respiratory depression, the leading cause of …
[HTML][HTML] L-cysteine ethylester reverses the adverse effects of morphine on breathing and arterial blood-gas chemistry while minimally affecting antinociception in …
L-cysteine ethylester (L-CYSee) is a membrane-permeable analogue of L-cysteine with a
variety of pharmacological effects. The purpose of this study was to determine the effects of L …
variety of pharmacological effects. The purpose of this study was to determine the effects of L …
Lipophilic analogues of D-cysteine prevent and reverse physical dependence to fentanyl in male rats
We examined whether co-injections of the cell-permeant D-cysteine analogues, D-cysteine
ethyl ester (D-CYSee) and D-cysteine ethyl amide (D-CYSea), prevent acquisition of …
ethyl ester (D-CYSee) and D-cysteine ethyl amide (D-CYSea), prevent acquisition of …
L-cysteine ethyl ester prevents and reverses acquired physical dependence on morphine in male Sprague Dawley rats
The molecular mechanisms underlying the acquisition of addiction/dependence on
morphine may result from the ability of the opioid to diminish the transport of L-cysteine into …
morphine may result from the ability of the opioid to diminish the transport of L-cysteine into …
Tropine exacerbates the ventilatory depressant actions of fentanyl in freely-moving rats
PM Getsy, WJ May, AP Young, SM Baby… - Frontiers in …, 2024 - frontiersin.org
Our lab is investigating the efficacy profiles of tropine analogs against opioid-induced
respiratory depression. The companion manuscript reports that the cell-permeant tropeine …
respiratory depression. The companion manuscript reports that the cell-permeant tropeine …
Fentanyl activates opposing opioid and non-opioid receptor systems that control breathing
SM Baby, WJ May, PM Getsy, GA Coffee… - Frontiers in …, 2024 - frontiersin.org
Fentanyl elicits profound disturbances in ventilatory control processes in humans and
experimental animals. The traditional viewpoint with respect to fentanyl-induced respiratory …
experimental animals. The traditional viewpoint with respect to fentanyl-induced respiratory …