Neuroprotective properties of berberine: Molecular mechanisms and clinical implications

E Tian, G Sharma, C Dai - Antioxidants, 2023 - mdpi.com
Berberine (BBR), an isoquinoline alkaloid natural product, is isolated primarily from Coptis
chinensis and other Berberis plants. BBR possesses various bioactivities, including …

Microglial cells: sensors for neuronal activity and microbiota-derived molecules

G D'Alessandro, F Marrocco, C Limatola - Frontiers in immunology, 2022 - frontiersin.org
Microglial cells play pleiotropic homeostatic activities in the brain, during development and
in adulthood. Microglia regulate synaptic activity and maturation, and continuously patrol …

Genetic engineering contribution to developing cyanobacteria-based hydrogen energy to reduce carbon emissions and establish a hydrogen economy

GK Kamshybayeva, BD Kossalbayev… - International Journal of …, 2024 - Elsevier
Growing concerns over greenhouse gas emissions and energy insecurity caused by the
depletion of conventional fuels have led to a search for sustainable fuel alternatives. As an …

Exploring the potential of vagus nerve stimulation in treating brain diseases: a review of immunologic benefits and neuroprotective efficacy

Z Jin, J Dong, Y Wang, Y Liu - European Journal of Medical Research, 2023 - Springer
The vagus nerve serves as a critical connection between the central nervous system and
internal organs. Originally known for its effectiveness in treating refractory epilepsy, vagus …

Neuromodulation and the Gut–Brain Axis: Therapeutic Mechanisms and Implications for Gastrointestinal and Neurological Disorders

B Aljeradat, D Kumar, S Abdulmuizz, M Kundu… - Pathophysiology, 2024 - mdpi.com
The gut–brain axis (GBA) represents a complex, bidirectional communication network that
intricately connects the gastrointestinal tract with the central nervous system (CNS) …

Gut brain interaction theory reveals gut microbiota mediated neurogenesis and traditional Chinese medicine research strategies

C Zhang, P Xue, H Zhang, C Tan, S Zhao… - Frontiers in Cellular …, 2022 - frontiersin.org
Adult neurogenesis is the process of differentiation of neural stem cells (NSCs) into neurons
and glial cells in certain areas of the adult brain. Defects in neurogenesis can lead to …

[HTML][HTML] Gut Metabolites Acting on the Gut-Brain Axis: Regulating the Functional State of Microglia

W Deng, P Yi, Y Xiong, J Ying, Y Lin, Y Dong… - Aging and …, 2024 - ncbi.nlm.nih.gov
The gut-brain axis is a communication channel that mediates a complex interplay of
intestinal flora with the neural, endocrine, and immune systems, linking gut and brain …

Interventional strategies for ischemic stroke based on the modulation of the gut microbiota

J Wang, X Liu, Q Li - Frontiers in Neuroscience, 2023 - frontiersin.org
The microbiota-gut-brain axis connects the brain and the gut in a bidirectional manner. The
organism's homeostasis is disrupted during an ischemic stroke (IS). Cerebral ischemia …

Microglia in Microbiota-Gut-Brain Axis: A Hub in Epilepsy

Y Liu, N Jia, C Tang, H Long, J Wang - Molecular Neurobiology, 2024 - Springer
There is growing concern about the role of the microbiota-gut-brain axis in neurological
illnesses, and it makes sense to consider microglia as a critical component of this axis in the …

The Gut Microbiome Controls Liver Tumors via the Vagus Nerve

KC Bauer, R Trehan, B Ruf, Y Myojin, MR Benmebarek… - bioRxiv, 2024 - biorxiv.org
Liver cancer ranks amongst the deadliest cancers. Nerves have emerged as an
understudied regulator of tumor progression. The parasympathetic vagus nerve influences …