Neurodegenerative diseases have reached alarming numbers in the past decade.
Unfortunately, clinical trials testing potential therapeutics have proven futile. In the absence …

It will be important to better characterize the presymptomatic period moving forward and
develop robust biomarkers that can be used both for stratification and outcome measures in …

Neurodegenerative diseases (NDs) represent an unsolved problem to date with an
everincreasing population incidence. Particularly, Alzheimer's disease (AD) is the most …

As our population ages, there is interest in delaying or intervening in cognitive decline.
While newer agents are under development, agents in mainstream use do not impact the …

Introduction The relation between traumatic brain injury (TBI), its acute and chronic
symptoms, and the potential for remote neurodegenerative disease is a priority for military …

Frontotemporal degeneration (FTD) is a common cause of young-onset dementia that is
characterized by progressive neurodegeneration in the frontal and temporal lobes of the …

Background Frontotemporal lobe disorders (FTD) are amongst the most common brain
neurodegenerative disorders. Their relatively covert, frequently subtle presentations and …

Methods: Participants were enrolled through the ARTFL/LEFFTDS Longitudinal
Frontotemporal Lobar Degeneration (ALLFTD) study, which includes symptomatic and …

Physical exercise is well known for its benefits on brain health. However, the mechanisms
through which these benefits occur remain discussed, especially in the context of cognitive …

Objectives: In healthy aging, the way people cope differently with cognitive and neural
decline is influenced by exposure to cognitively enriching life-experiences. Education is one …