[HTML][HTML] Targeting cancer hallmarks with epigallocatechin gallate (EGCG): mechanistic basis and therapeutic targets

WH Talib, D Awajan, A Alqudah, R Alsawwaf… - Molecules, 2024 - mdpi.com
Epigallocatechin gallate (EGCG) is a catechin, which is a type of flavonoid found in high
concentrations in green tea. EGCG has been studied extensively for its potential health …

[HTML][HTML] Telomerase Inhibition in the Treatment of Leukemia: A Comprehensive Review

E Bartoszewska, K Molik, M Woźniak, A Choromańska - Antioxidants, 2024 - mdpi.com
Leukemia, characterized by the uncontrolled proliferation and differentiation blockage of
myeloid or lymphoid precursor cells, presents significant therapeutic challenges despite …

Combinatorial targeting of telomerase and DNA-PK induces synergistic apoptotic effects against Pre-B acute lymphoblastic leukemia cells

M Katoueezadeh, P Maleki, SA Torabizadeh… - Molecular Biology …, 2024 - Springer
Background Due to the high demand for novel approaches for leukemia-targeted therapy,
this study investigates the impact of DNA-PK inhibitor NU7441 on the sensitivity of pre-B ALL …

[HTML][HTML] Causal association between telomere length and female reproductive endocrine diseases: a univariable and multivariable Mendelian randomization analysis

QR Yang, JF Zhang, ZL Fan - Journal of Ovarian Research, 2024 - Springer
Background The relationship between leukocyte telomere length (LTL) and female
reproductive endocrine diseases has gained significant attention and research interest in …

[PDF][PDF] Cellular Aging and Senescence in Cancer: A Holistic Review of Cellular Fate Determinants

M Tufail, YQ Huang, JJ Hu, J Liang, CY He… - Aging and …, 2025 - researchgate.net
This comprehensive review navigates the complex relationship between cellular aging,
senescence, and cancer, unraveling the determinants of cellular fate. Beginning with an …

[PDF][PDF] Research progress on natural products against hepatocellular carcinoma

L ZHANG, YAN LI, J MAO - Biocell, 2024 - cdn.techscience.cn
Hepatocellular carcinoma (HCC) remains a prevalent and challenging malignancy globally,
characterized by its numerous causal factors and generally unfavorable prognosis. In the …