Oxidative stress in obstructive sleep apnea and intermittent hypoxia–revisited–the bad ugly and good: implications to the heart and brain

L Lavie - Sleep medicine reviews, 2015 - Elsevier
Obstructive sleep apnea (OSA), characterized by intermittent hypoxia (IH), is linked with
increased reactive oxygen species/reactive nitrogen species (ROS/RNS) and oxidative …

Obstructive sleep apnoea syndrome

P Lévy, M Kohler, WT McNicholas, F Barbé… - Nature reviews Disease …, 2015 - nature.com
Obstructive sleep apnoea syndrome (OSAS) is a common clinical condition in which the
throat narrows or collapses repeatedly during sleep, causing obstructive sleep apnoea …

Molecular mechanisms of cardiovascular disease in OSAHS: the oxidative stress link

L Lavie, P Lavie - European Respiratory Journal, 2009 - Eur Respiratory Soc
Obstructive sleep apnoea/hypopnoea syndrome (OSAHS) is a highly prevalent breathing
disorder in sleep that is an independent risk factor for cardiovascular morbidity and mortality …

Cardiovascular disease in obstructive sleep apnoea syndrome: the role of intermittent hypoxia and inflammation

JF Garvey, CT Taylor… - European Respiratory …, 2009 - Eur Respiratory Soc
There is increasing evidence that intermittent hypoxia plays a role in the development of
cardiovascular risk in obstructive sleep apnoea syndrome (OSAS) through the activation of …

Chronic obstructive pulmonary disease and obstructive sleep apnea: overlaps in pathophysiology, systemic inflammation, and cardiovascular disease

WT McNicholas - American journal of respiratory and critical care …, 2009 - atsjournals.org
Chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea syndrome
represent two of the most prevalent chronic respiratory disorders in clinical practice, and …

Models of intermittent hypoxia and obstructive sleep apnea: molecular pathways and their contribution to cancer

I Hunyor, KM Cook - American Journal of Physiology …, 2018 - journals.physiology.org
Obstructive sleep apnea (OSA) is common and linked to a variety of poor health outcomes. A
key modulator of this disease is nocturnal intermittent hypoxia. There is striking …

[HTML][HTML] Technical feasibility and physiological relevance of hypoxic cell culture models

J Pavlacky, J Polak - Frontiers in endocrinology, 2020 - frontiersin.org
Hypoxia is characterized as insufficient oxygen delivery to tissues and cells in the body and
is prevalent in many human physiology processes and diseases. Thus, it is an attractive …

Role of polymorphonuclear neutrophils in atherosclerosis: current state and future perspectives

R Baetta, A Corsini - Atherosclerosis, 2010 - Elsevier
Contrary to the long-standing and widely accepted belief that polymorphonuclear
neutrophils (PMN) are of marginal relevance in atherosclerosis, evidence revealing a …

[PDF][PDF] Oxidative stress inflammation and endothelial dysfunction in obstructive sleep apnea

L Lavie - Frontiers in Bioscience-Elite, 2012 - academia.edu
Introduction 3. Association of OSA with cardiovascular morbidity 3.1. Prevailing mechanisms
4. Oxidative stress in OSA 4.1. Consequences of oxidative stress 4.2. Reactive oxygen …

Sleep, sleep disorders and inflammation in children

D Gozal - Sleep medicine, 2009 - Elsevier
Sleep-disordered breathing (SDB) and, more specifically, obstructive sleep apnea (OSA),
can lead to significant morbidities including cardiovascular morbidity and neurocognitive …