Well designed epidemiological studies on hypersensitivity drug reactions are lacking as
most studies have been on adverse drug reactions. Such studies will be helpful in identifying …

According to the National Health and Nutrition Examination Survey 2012, one third of
antihypertensive prescriptions in the United States in the past decade were for angiotensin …

1.1 Background Patients with cough frequently present to clinicians working in both primary
and secondary care. 1, 2 Acute cough, which often follows an upper respiratory tract …

Background Although certain drugs that target the renin-angiotensin-aldosterone system are
linked to an increased risk for angioedema, data on their absolute and comparative risks are …

Angioedema is a rare but potentially serious complication of angiotensin-converting enzyme
inhibitor (ACE) use. We conducted a study to estimate incidence of ACE-related …

Bradykinin (BK) metabolism and its receptors play a central role in drug-induced
angioedema (AE) without urticaria through increased vascular permeability. Many …

Background Blood pressure (BP) control and reduction of urinary protein excretion using
agents that block the renin–angiotensin aldosterone system are the mainstay of therapy for …

Objective: To review current guidelines and recent data evaluating the efficacy and safety of
angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs) …

Angiotensin-converting enzyme inhibitors (ACE-I) are widely used in diseases, such as
hypertension, congestive heart failure, and myocardial infarction. Although these drugs are …

Angiotensin-converting enzyme (ACE, kininase II) inhibitors reduce mortality in patients who
have hypertension, congestive heart failure, and diabetic nephropathy and in patients who …