Exposure of rodents to an enriched environment (EE) has been shown to reliably increase
performance on hippocampus-dependent learning and memory tasks, compared to …

Abstract Environmental enrichment (“EE”) is expected to alleviate the negative effects of
stress on cognitive performance. However, there are complexities associated with …

Several studies have shown that manipulations to the housing environment modulate
susceptibility to stress in laboratory animals, mainly in rodents. Environmental enrichment …

Stress exposure can produce profound changes in physiology and behavior that can impair
health and well-being. Of note, stress exposure is linked to anxiety disorders and depression …

Anxiety disorders are currently a major psychiatric and social problem, the mechanisms of
which have been only partially elucidated. The hippocampus serves as a major target of …

Environmental enrichment (EE) is an environmental paradigm encompassing sensory,
cognitive, and physical stimulation at a heightened level. Previous studies have reported the …

Severe and prolonged stress is the main environmental factor that precipitates depression,
anxiety and cognitive dysfunctions. On the other hand, exposure to environmental …

Although numerous studies have indicated that chronic stress causes cognitive dysfunction
with the impairment of synaptic structures and functions, the relationship between cognitive …

The G protein-coupled receptor 55 (GPR55) is a novel cannabinoid receptor, whose exact
role in anxiety remains unknown. The present study was conducted to explore the possible …

Epilepsy is a neurological condition associated with seizures, neurodegeneration, circuit
reorganization, and other structural and functional abnormalities. These elements ultimately …