20-week study of clinical outcomes of over-the-counter COVID-19 prophylaxis and treatment

L Margolin, J Luchins, D Margolin… - Journal of evidence …, 2021 - journals.sagepub.com
Objectives and Setting. As the lethal COVID-19 pandemic enters its second year, the need
for effective modalities of alleviation remains urgent. This includes modalities that can …

Quercetin and iron metabolism: What we know and what we need to know

L Xiao, G Luo, Y Tang, P Yao - Food and chemical toxicology, 2018 - Elsevier
Iron is a life-supporting micronutrient that is required in the human diet, and is essential for
maintaining physiological homeostasis. Properly harnessing a redox-active metal such as …

Quercetin preserves oral cavity health by mitigating inflammation and microbial dysbiosis

EC Mooney, SE Holden, XJ Xia, Y Li, M Jiang… - Frontiers in …, 2021 - frontiersin.org
Failure to attenuate inflammation coupled with consequent microbiota changes drives the
development of bone-destructive periodontitis. Quercetin, a plant-derived polyphenolic …

Quercetin protects cardiomyocytes against doxorubicin-induced toxicity by suppressing oxidative stress and improving mitochondrial function via 14-3-3γ

X Chen, X Peng, Y Luo, J You, D Yin, Q Xu… - Toxicology …, 2019 - Taylor & Francis
Cardiotoxicity limits the clinical applications of doxorubicin (Dox), which mechanism might
be excess generation of intracellular ROS. Quercetin (Que) is a flavonoid that possesses …

Effects of quercetin supplementation on glycemic control among patients with metabolic syndrome and related disorders: A systematic review and meta‐analysis of …

V Ostadmohammadi, A Milajerdi, E Ayati… - Phytotherapy …, 2019 - Wiley Online Library
This systematic review and meta‐analysis of randomized controlled trials was performed to
determine the effect of quercetin supplementation on glycemic control among patients with …

Quercetin prevents cadmium chloride‐induced hepatic steatosis and fibrosis by downregulating the transcription of miR‐21

GM Alshammari, WH Al‐Qahtani, NA AlFaris… - …, 2021 - Wiley Online Library
This study investigated if cadmium chloride (CdCl2)‐induced hepatic steatosis and fibrosis
and the protective effect of quercetin (QUR) are mediated modulating the activity of miR‐21 …

Phytonutrients: Sources, bioavailability, interaction with gut microbiota, and their impacts on human health

J Kan, F Wu, F Wang, J Zheng, J Cheng, Y Li… - Frontiers in …, 2022 - frontiersin.org
Phytonutrients are natural bioactive components present in the daily diet that can exert a
positive impact on human health. Studies have shown that phytonutrients may act as …

Garlic consumption in relation to colorectal cancer risk and to alterations of blood bacterial DNA

MC Speciani, G Gargari, R Penagini… - European Journal of …, 2023 - Springer
Purpose Garlic consumption has been inversely associated to intestinal adenoma (IA) and
colorectal cancer (CRC) risk, although evidence is not consistent. Gut microbiota has been …

Current evidence to support the therapeutic potential of flavonoids in oxidative stress-related dermatoses

D Xian, M Guo, J Xu, Y Yang, Y Zhao, J Zhong - Redox report, 2021 - Taylor & Francis
Background Skin, as a crucial external defense organ, is more vulnerable to oxidative stress
(OS) insult, reactive oxygen species (ROS)-mediated OS in particular. OS results from a …

Prediction of new targets and mechanisms for quercetin in the treatment of pancreatic cancer, colon cancer, and rectal cancer

B Pang, X Xu, Y Lu, H Jin, R Yang, C Jiang, D Shao… - Food & function, 2019 - pubs.rsc.org
Quercetin has been widely found to exhibit anticancer activity with low toxicity and
prevalence in foods. Quercetin has been reported to inhibit digestive system cancers …