Duchenne muscular dystrophy (DMD) is an X-linked muscle-wasting disease caused by the
loss of dystrophin. DMD is associated with muscle degeneration, necrosis, inflammation …

Skeletal muscle constitutes∼ 40% of body mass and has the capacity to play a major role as
thermogenic, metabolic, and endocrine organ. In addition to shivering, muscle also …

Duchenne muscular dystrophy (DMD) is caused by the absence of the dystrophin protein
and a properly functioning dystrophin-associated protein complex (DAPC) in muscle cells …

Sarcolipin (SLN) is an inhibitor of the sarco/endoplasmic reticulum (SR) Ca2+ ATPase
(SERCA) and is abnormally elevated in the muscle of Duchenne muscular dystrophy (DMD) …

Duchenne muscular dystrophy (DMD) is a progressive disease caused by the loss of
function of the protein dystrophin. This protein contributes to the stabilisation of striated cells …

Sarcolipin (SLN) is a small regulatory protein that inhibits the sarco (endo) plasmic reticulum
Ca2+-ATPase (SERCA) pump. When bound to SERCA, SLN reduces the apparent Ca2+ …

The sarco-endoplasmic reticulum calcium ATPase (SERCA) is responsible for maintaining
calcium homeostasis in all eukaryotic cells by actively transporting calcium from the cytosol …

Duchenne muscular dystrophy (DMD) is an X-linked genetic disorder characterized by
progressive muscular weakness because of the loss of dystrophin. Extracellular Ca2+ flows …

Background We have previously shown that the deletion of the superoxide scavenger, CuZn
superoxide dismutase, in mice (Sod1−/− mice) results in increased oxidative stress and an …

Abstract In muscle, the Sarco (Endo) plasmic Reticulum Calcium ATPase (SERCA) activity is
regulated by two distinct proteins, PLB and SLN, which are highly conserved throughout …