The cellular barriers are major bottlenecks for bioactive compounds entering into cells to
accomplish their biological functions, which limits their biomedical applications …

The coronavirus (COVID-19) pandemic has underscored the critical role of mRNA-based
vaccines as powerful, adaptable, readily manufacturable, and safe methodologies for …

Determination of drug solubility in supercritical solvents such as CO 2 has been of great
importance for preparation of nanomedicines. This study implements and tunes several …

Nanozyme catalytic therapy for cancer treatments has become one of the heated topics, and
the therapeutic efficacy is highly correlated with their catalytic efficiency. In this work, three …

Riluzole is commonly used as a neuroprotective agent for treating traumatic spinal cord
injury (SCI), which works by blocking the influx of sodium and calcium ions and reducing …

Particle-based drug delivery systems have shown promising application potential to treat
human diseases; however, an incomplete understanding of their interactions with vascular …

Background: Nanotechnology has been increasingly used in healthcare during recent years.
However, the systematic evaluation of research on nanotechnology for pain management is …

The effects of dendron side chains in polymeric conjugates on tumor penetration and
antigen presentation are systematically examined. Three polymergemcitabine (Gem) …

Renal cell carcinoma (RCC) is a hot tumor infiltrated by large numbers of CD8+ T cells and
is highly sensitive to immunotherapy. However, tumorassociated macrophages (TAMs) …

Metastasis and recurrence are notable contributors to mortality associated with breast
cancer. Although immunotherapy has shown promise in mitigating these risks after …