Idiopathic nephrotic syndrome newly affects 1–3 per 100,000 children per year.
Approximately 85% of cases show complete remission of proteinuria following …

Minimal change disease (MCD) is a major cause of idiopathic nephrotic syndrome (NS),
characterized by intense proteinuria leading to edema and intravascular volume depletion …

Results Steroid-resistant nephrotic syndrome manifested in the first 5 years of life in 64% of
the patients. Congenital nephrotic syndrome accounted for 6% of all patients. Extrarenal …

The pathogenesis of nephrotic syndrome is unclear. However, the efficacy of rituximab, a B
cell–depleting antibody, in nephrotic syndrome suggests a pathogenic role of B cells. In this …

Background and objectives: Mutations in podocyte genes are associated with steroid-
resistant nephrotic syndrome (SRNS), mostly affecting younger age groups. To date, it is …

Idiopathic nephrotic syndrome is the most common glomerular disease in children.
Corticosteroids are the cornerstone of its treatment, and steroid response is the main …

Abstract Kidney Disease: Improving Global Outcomes (KDIGO) recently published the
clinical practice guideline on glomerulonephritis (GN) to assist the practitioner caring for …

BACKGROUND: To examine whether tacrolimus is more effective and safe than
cyclosporine (CsA) in inducing remission in patients with steroid-resistant nephrotic …

Prolonged prednisolone treatment for the initial episode of childhood nephrotic syndrome
may reduce relapse rate, but whether this results from the increased duration of treatment or …

The aim of this study was to establish the efficacy and safety of rituximab in refractory
nephrotic syndrome (NS). Members of the International Paediatric Nephrology Association …