[HTML][HTML] Polycystic ovary syndrome: pathophysiology and therapeutic opportunities

J Dong, DA Rees - BMJ medicine, 2023 - ncbi.nlm.nih.gov
Polycystic ovary syndrome is characterised by excessive levels of androgens and ovulatory
dysfunction, and is a common endocrine disorder in women of reproductive age. Polycystic …

[HTML][HTML] Therapeutic effects and molecular mechanism of chlorogenic acid on polycystic ovarian syndrome: role of HIF-1alpha

Z Zhang, C Shi, Z Wang - Nutrients, 2023 - mdpi.com
Chlorogenic acid (CGA) is a powerful antioxidant polyphenol molecule found in many diets
and liquid beverages, playing a preventive and therapeutic role in various diseases caused …

[HTML][HTML] Androgen excess: a hallmark of polycystic ovary syndrome

K Wang, Y Li, Y Chen - Frontiers in Endocrinology, 2023 - frontiersin.org
Polycystic ovarian syndrome (PCOS) is a metabolic, reproductive, and psychological
disorder affecting 6–20% of reproductive women worldwide. However, there is still no cure …

[HTML][HTML] Physical exercise alleviates oxidative stress in brown adipose tissue and causes changes in body composition and nutritional behavior in rats with polycystic …

WLL Santos, C da Silva Pinheiro, R de Oliveira Santos… - Life Sciences, 2023 - Elsevier
Abstract Aim Polycystic Ovary Syndrome (PCOS) is a very common endocrine disorder in
women. We investigate the effect of physical exercise on body composition, nutritional …

[HTML][HTML] Induced Pluripotent Stem Cells as a Possible Approach for Exploring the Pathophysiology of Polycystic Ovary Syndrome (PCOS)

M Khatun, K Lundin, F Naillat, L Loog… - Stem cell reviews and …, 2024 - Springer
Polycystic ovary syndrome (PCOS) is the most prevalent endocrine condition among women
with pleiotropic sequelae possessing reproductive, metabolic, and psychological …

Roxadustat alleviates metabolic traits in letrozole-induced PCOS mice

N Virtanen, U Saarela, M Karpale, R Arffman… - Biochemical …, 2024 - Elsevier
Polycystic ovary syndrome (PCOS) is a highly prevalent disorder in women that is commonly
accompanied by metabolic syndrome. Activation of the hypoxia-inducible factor (HIF) …

Brown adipose tissue‐derived exosomes improve polycystic ovary syndrome in mice via STAT3/GPX4 signaling pathway

YQ Fang, HK Zhang, QQ Wei, YH Li - The FASEB Journal, 2024 - Wiley Online Library
Polycystic ovary syndrome (PCOS) is associated with impaired adipose tissue physiology.
Elevated brown adipose tissue (BAT) mass or activity has shown potential in the treatment of …

[HTML][HTML] Balancing Act: Exploring the Gut Microbiota-Brown Adipose Tissue Axis in PCOS Pathogenesis and Therapeutic Frontiers

Y Li, Y Fang, H Wang, H Zhang - Frontiers in Bioscience-Landmark, 2024 - imrpress.com
Polycystic ovary syndrome (PCOS) is a prevalent reproductive, endocrine, and metabolic
disease that affects 5–18% of women worldwide, with a rising incidence …

[PDF][PDF] Therapeutic effects and molecular mechanism of chlorogenic acid on polycystic ovarian syndrome: role of HIF-1alpha. Nutrients 2023; 15: 2833

Z Zhang, C Shi, Z Wang - 2023 - pdfs.semanticscholar.org
Chlorogenic acid (CGA) is a powerful antioxidant polyphenol molecule found in many diets
and liquid beverages, playing a preventive and therapeutic role in various diseases caused …

[PDF][PDF] Correlations between beclin-1 and transforming growth factor-β1 in letrozole induced polycystic ovary syndrome.

NM Hamdy, HM Ghanem, MM Mohamed… - Indian Journal of …, 2024 - researchgate.net
In the pathogenesis of polycystic ovary syndrome (PCOS), despite the importance of
autophagy and transforming growth factor-β1 (TGF-β1), there is scarce information about …