Efficacy and safety of spesolimab for the management of generalized pustular psoriasis: a drug safety evaluation

L Potestio, E Camela, S Cacciapuoti… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction Generalized pustular psoriasis (GPP) is a rare form of psoriasis (less of 1% of
cases). Currently, GPP is recognized as a clinical entity, distinguished from plaque psoriasis …

The Role of Interleukin 23/17 Axis in Psoriasis Management: A Comprehensive Review of Clinical Trials

L Potestio, F Martora, G Lauletta, Y Vallone… - Clinical, Cosmetic …, 2024 - Taylor & Francis
Psoriasis pathogenesis is influenced by genetic factors and characterized by a complex
interplay between genetic predisposition and various environmental triggers. These triggers …

Psoriasis and Molecular Target Therapies: Evidence of Efficacy in Preventing Cardiovascular Comorbidities

L Potestio, N Tommasino, G Lauletta, F Martora… - Dermatology and …, 2024 - Springer
Psoriasis is now considered a systemic disease, and several comorbidities have been
described such as cardiovascular diseases, neurologic and psychiatric disorders, chronic …

JAK Inhibitors in Psoriatic Disease

M Megna, L Potestio, A Ruggiero… - Clinical, Cosmetic …, 2023 - Taylor & Francis
Psoriasis is now considered to be the cutaneous phenotype of a systemic inflammatory
condition, recognized under the term Psoriatic Disease (PsD). PsD has several …

Drug survival of IL-12/23, IL-17 and IL-23 inhibitors for moderate-to-severe plaque psoriasis: a retrospective multicenter real-world experience on 5932 treatment …

L Gargiulo, L Ibba, P Malagoli, A Balato… - Frontiers in …, 2024 - frontiersin.org
Introduction The development of several effective biological drugs for moderate-to-severe
plaque psoriasis has dramatically changed the lives of patients. Despite the wide use of …

[HTML][HTML] Bimekizumab for the Treatment of Plaque Psoriasis With Involvement of Genitalia: A 16-Week Multicenter Real-World Experience—IL PSO (Italian Landscape …

D Orsini, P Malagoli, A Balato, L Bianchi… - Dermatology Practical …, 2024 - ncbi.nlm.nih.gov
Objectives We aimed to determine the effectiveness profile of bimekizumab in patients
affected by moderate-to-severe plaque psoriasis with involvement of genitalia. Methods …

Real‐world effectiveness and safety of bimekizumab in Japanese patients with psoriasis: A single‐center retrospective study

T Hagino, H Saeki, E Fujimoto… - The Journal of …, 2024 - Wiley Online Library
Bimekizumab, which suppresses both interleukin (IL)‐17A and IL‐17F, has recently been
approved as a biologic for psoriasis. We aimed to evaluate the real‐world effectiveness and …

Efficacy and safety of deucravacitinib for the management of psoriasis: a drug safety evaluation

L Potestio, N Tommasino, G Lauletta… - Expert Opinion on …, 2024 - Taylor & Francis
Introduction Nowadays, despite the wide availability of biological drugs and apremilast for
psoriasis management, there is always a need for new therapies to customize the …

Generalized Pustular Psoriasis and Systemic Organ Dysfunctions

R Teshima, N Saito-Sasaki, Y Sawada - International Journal of …, 2024 - mdpi.com
This review explores the intricate relationship between generalized pustular psoriasis (GPP)
and various systemic diseases, shedding light on the broader impacts of this severe skin …

Management of Psoriasis Patients with Serious Infectious Diseases

M Megna, G Lauletta, N Tommasino, A Salsano… - Advances in …, 2024 - Springer
The management of patients affected by moderate-to-severe psoriasis may be challenging,
in particular in patients with serious infectious diseases [tuberculosis (TB), hepatitis B and C …