Hereditary Angioedema Hereditary angioedema is a rare genetic disease that may include
recurrent attacks of cutaneous angioedema, severe abdominal pain, and airway …

Background Angioedema is a common presentation in the emergency department (ED).
Airway angioedema can be fatal; therefore, prompt diagnosis and correct treatment are vital …

Hereditary Angioedema (HAE) is a rare and disabling disease. Early diagnosis and
appropriate therapy are essential. This update and revision of the global guideline for HAE …

Background Guidelines recommend effective on-demand therapy for all individuals with
hereditary angioedema. We aimed to assess the novel oral plasma kallikrein inhibitor …

Complement deficiencies comprise between 1 and 10% of all primary immunodeficiencies
(PIDs) according to national and supranational registries. They are still considered rare and …

Angioedema is defined by non-dependent, non-pitting edema that affects several different
sites and is potentially life-threatening due to laryngeal edema. This narrative review …

Background Upper airway angioedema is a rare, unpredictable, and at times life-threatening
adverse effect of angiotensin-converting enzyme inhibitors (ACE-Is) with no existing effective …

Despite its relatively common occurrence and life‐threatening potential, the management of
angioedema in the emergency department (ED) is lacking in terms of a structured approach …

In recent years, complement analysis of body fluids and biopsies, going far beyond C3 and
C4, has significantly enhanced our understanding of the disease process. Such expanded …

Abstract Background/Objectives Melasma is a common acquired hyperpigmentary disorder,
particularly among Asians and Hispanics, but its exact pathomechanism is poorly …