Demethylzeylasteral protects against renal interstitial fibrosis by attenuating mitochondrial complex I-mediated oxidative stress
P Shen, X Deng, T Li, X Chen, X Wu - Journal of Ethnopharmacology, 2024 - Elsevier
Ethnopharmacological relevance Renal interstitial fibrosis (RIF) is a main pathological
process in chronic kidney disease (CKD). Demethylzeylasteral (DML), a major component of …
process in chronic kidney disease (CKD). Demethylzeylasteral (DML), a major component of …
[HTML][HTML] Demethylzeylasteral exerts potent efficacy against non-small-cell lung cancer via the P53 signaling pathway
L Lv, F Zhou, Y Quan, Y Fan, Y Bao, Y Dou, H Qu… - Translational …, 2024 - Elsevier
Lung cancer has one of the highest mortality rates worldwide, with non-small-cell lung
cancer (NSCLC) constituting approximately 85% of all cases. Demethylzeylasteral (DEM) …
cancer (NSCLC) constituting approximately 85% of all cases. Demethylzeylasteral (DEM) …
Virtual screening of natural products targeting ubiquitin-specific protease 7
H Li, Y Sun, H Yin, Y Zhang, J Yu, N Hou… - Journal of …, 2024 - Taylor & Francis
Abstract Ubiquitin-specific protease 7 (USP7) is a promising prognostic and druggable
target for cancer therapy. Inhibition of USP7 can activate the MDM2-P53 signaling pathway …
target for cancer therapy. Inhibition of USP7 can activate the MDM2-P53 signaling pathway …