The protein corona from nanomedicine to environmental science

M Mahmoudi, MP Landry, A Moore… - Nature Reviews Materials, 2023 - nature.com
The protein corona spontaneously develops and evolves on the surface of nanoscale
materials when they are exposed to biological environments, altering their physiochemical …

'Passive'nanoparticles for organ-selective systemic delivery: design, mechanism and perspective

L Fu, Y Zhang, RA Farokhzad, BB Mendes… - Chemical Society …, 2023 - pubs.rsc.org
Nanotechnology has shown tremendous success in the drug delivery field for more effective
and safer therapy, and has recently enabled the clinical approval of RNA medicine, a new …

Cholesterol modulates the physiological response to nanoparticles by changing the composition of protein corona

H Tang, Y Zhang, T Yang, C Wang, Y Zhu, L Qiu… - Nature …, 2023 - nature.com
Nanoparticles (NPs) in biological fluids form a layer of biomolecules known as the protein
corona. The protein corona has been shown to determine the biological identity and in vivo …

Covalent Organic Framework Nanobowls as Activatable Nanosensitizers for Tumor‐Specific and Ferroptosis‐Augmented Sonodynamic Therapy

S Zhang, S Xia, L Chen, Y Chen, J Zhou - Advanced Science, 2023 - Wiley Online Library
Covalent organic frameworks (COFs) have attracted increasing attention for biomedical
applications. COFs‐based nanosensitizers with uniform nanoscale morphology and tumor …

Regulation of protein corona on liposomes using albumin-binding peptide for targeted tumor therapy

H Li, D Yin, J Liao, Y Wang, R Gou, C Tang, W Li… - Journal of Controlled …, 2023 - Elsevier
Nanocarriers entering the body are usually coated by plasma protein, leading to a protein
“corona” easily recognized by tissues and cells. Adjusting the composition of protein …

Engineering nanomaterial physical characteristics for cancer immunotherapy

DY Lee, K Huntoon, J Lux, BYS Kim… - Nature Reviews …, 2023 - nature.com
The physical properties of nanomaterials—such as size, structure, shape, charge,
mechanical strength and hydrophobicity—can directly or indirectly influence immune cell …

Interface Assembly of Polymer Networks on Metal–Organic Frameworks for the Engineering of Functional Nanoparticles

Y Tian, Z Gao, M Li, M Hu, J Hao, J Cui - Chemistry of Materials, 2023 - ACS Publications
We report a versatile approach for the engineering of functional polymer nanoparticles (NPs)
with tunable sizes, stiffness, and responsiveness via templating zeolitic imidazolate …

Biological features of nanoparticles: protein corona formation and interaction with the immune system

S Panico, S Capolla, S Bozzer, G Toffoli, M Dal Bo… - Pharmaceutics, 2022 - mdpi.com
Nanoparticles (NPs) are versatile candidates for nanomedical applications due to their
unique physicochemical properties. However, their clinical applicability is hindered by their …

Optimization of iron oxide nanoparticles for MRI-guided magnetic hyperthermia tumor therapy: reassessing the role of shape in their magnetocaloric effect

JM Paez-Muñoz, F Gámez… - Journal of Materials …, 2023 - pubs.rsc.org
Superparamagnetic iron oxide nanoparticles have hogged the limelight in different fields of
nanotechnology. Surprisingly, notwithstanding the prominent role played as agents in …

The effect of elasticity of gelatin nanoparticles on the interaction with macrophages

M Yildirim, AV Weiss, M Schneider - Pharmaceutics, 2023 - mdpi.com
Gelatin is a biocompatible, biodegradable, cheap, and nontoxic material, which is already
used for pharmaceutical applications. Nanoparticles from gelatin (GNPs) are considered a …