Dry eye disease and blinking behaviors: A narrative review of methodologies for measuring blink dynamics and inducing blink response

A Oganov, G Yazdanpanah, S Jabbehdari… - The Ocular Surface, 2023 - Elsevier
Dry eye disease (DED) is a leading cause of ophthalmology clinical encounters with
prevalence ranging from 8.7% to 64% in various populations. Blinking is an endogenous …

Smartphone-based digital phenotyping for dry eye toward P4 medicine: a crowdsourced cross-sectional study

T Inomata, M Nakamura, J Sung… - NPJ Digital …, 2021 - nature.com
Multidimensional integrative data analysis of digital phenotyping is crucial for elucidating the
pathologies of multifactorial and heterogeneous diseases, such as the dry eye (DE). This …

Detecting dry eye from ocular surface videos based on deep learning

H Abdelmotaal, R Hazarbasanov, S Taneri… - The ocular …, 2023 - Elsevier
Objective To assess the performance of convolutional neural networks (CNNs) for
automated diagnosis of dry eye (DE) in patients undergoing video keratoscopy based on …

DryEyeRhythm: A reliable and valid smartphone application for the diagnosis assistance of dry eye

Y Okumura, T Inomata, A Midorikawa-Inomata, J Sung… - The Ocular Surface, 2022 - Elsevier
Purpose Undiagnosed or inadequately treated dry eye disease (DED) decreases the quality
of life. We aimed to investigate the reliability, validity, and feasibility of the DryEyeRhythm …

Tear film break-up time and dry eye disease severity in a large Norwegian cohort

M Yazdani, J Fiskådal, X Chen, ØA Utheim… - Journal of Clinical …, 2021 - mdpi.com
This study evaluated to what extent tear film break-up time (TFBUT) could discriminate
pathological scores for other clinical tests and explore the associations between them. Dry …

Cross-hierarchical integrative research network for heterogenetic eye disease toward P4 medicine: a narrative review

T INOMATA, J SUNG, M NAKAMURA… - Juntendo Medical …, 2021 - jstage.jst.go.jp
Society 5.0, a visionary human-centered societal model, fuels economic development and
resolves long-standing social problems. The model establishes a technological foundation …

[HTML][HTML] Diagnostic ability of a smartphone app for dry eye disease: protocol for a multicenter, open-label, prospective, and cross-sectional study

K Nagino, Y Okumura, M Yamaguchi… - JMIR Research …, 2023 - researchprotocols.org
Background Dry eye disease (DED) is one of the most common ocular surface diseases.
Numerous patients with DED remain undiagnosed and inadequately treated, experiencing …

Video-based eye blink identification and classification

G Nousias, EK Panagiotopoulou… - IEEE Journal of …, 2022 - ieeexplore.ieee.org
Blink detection and classification can provide a very useful clinical indicator, because of its
relation with many neurological and ophthalmological conditions. In this work, we propose a …

Clinical efficacy of Diquafosol sodium 3% versus Hyaluronic acid 0.1% in patients with dry eye disease after cataract surgery: a protocol for a single-centre …

M Miura, T Inomata, S Nojiri, J Sung, M Nagao… - BMJ open, 2022 - bmjopen.bmj.com
Introduction The number of cataract surgeries, the most common ophthalmic surgery, is
expected to increase due to ageing populations. Dry eye disease (DED) is a frequent side …

Camera-based blink detection using 3d-landmarks

D Kraft, F Hartmann, G Bieber - … of the 7th International Workshop on …, 2022 - dl.acm.org
Working in front of the computer for long periods of time leads to exhaustion, fatigue and
high strain on the eyes. Often the natural eye blink activity is disturbed and the eyes do not …