[HTML][HTML] An overview of bioinformatics tools for epitope prediction: implications on vaccine development

RE Soria-Guerra, R Nieto-Gomez… - Journal of biomedical …, 2015 - Elsevier
Exploitation of recombinant DNA and sequencing technologies has led to a new concept in
vaccination in which isolated epitopes, capable of stimulating a specific immune response …

BIOPEP database and other programs for processing bioactive peptide sequences

P Minkiewicz, J Dziuba, A Iwaniak… - Journal of AOAC …, 2008 - academic.oup.com
This review presents the potential for application of computational tools in peptide science
based on a sample BIOPEP database and program as well as other programs and …

Design of a multiepitope‐based peptide vaccine against the e protein of human COVID‐19: an immunoinformatics approach

MI Abdelmageed, AH Abdelmoneim… - BioMed research …, 2020 - Wiley Online Library
Background. A new endemic disease has spread across Wuhan City, China, in December
2019. Within few weeks, the World Health Organization (WHO) announced a novel …

A guide to current methodology and usage of reverse vaccinology towards in silico vaccine discovery

SJ Goodswen, PJ Kennedy… - FEMS Microbiology …, 2023 - academic.oup.com
Reverse vaccinology (RV) was described at its inception in 2000 as an in silico process that
starts from the genomic sequence of the pathogen and ends with a list of potential protein …

Immunoinformatics Approach for Epitope‐Based Peptide Vaccine Design and Active Site Prediction against Polyprotein of Emerging Oropouche Virus

UK Adhikari, M Tayebi… - Journal of immunology …, 2018 - Wiley Online Library
Oropouche virus (OROV) is an emerging pathogen which causes Oropouche fever and
meningitis in humans. Several outbreaks of OROV in South America, especially in Brazil …

Immunoinformatics: In Silico Approaches and Computational Design of a Multi-epitope, Immunogenic Protein

AA Bahrami, Z Payandeh, S Khalili… - International reviews …, 2019 - Taylor & Francis
Immunoinformatics is a new critical field with several tools and databases that conduct the
eyesight of experimental selection and facilitate analysis of the great amount of immunologic …

A review of the infection, genetics, and evolution of Neospora caninum: from the past to the present

SJ Goodswen, PJ Kennedy, JT Ellis - Infection, Genetics and Evolution, 2013 - Elsevier
This paper is a review of current knowledge on Neospora caninum in the context of other
apicomplexan parasites and with an emphasis on: life cycle, disease, epidemiology …

Recent advances in B-cell epitope prediction methods

Y El-Manzalawy, V Honavar - Immunome research, 2010 - Springer
Identification of epitopes that invoke strong responses from B-cells is one of the key steps in
designing effective vaccines against pathogens. Because experimental determination of …

An introduction to epitope prediction methods and software

X Yang, X Yu - Reviews in medical virology, 2009 - Wiley Online Library
In this paper, current prediction methods and algorithms for both T‐and B cell epitopes are
reviewed, and a comprehensive summary of epitope prediction software and databases …

Immunogenicity of biologically-derived therapeutics: assessment and interpretation of nonclinical safety studies

R Ponce, L Abad, L Amaravadi, T Gelzleichter… - Regulatory Toxicology …, 2009 - Elsevier
An evaluation of potential antibody formation to biologic therapeutics during the course of
nonclinical safety studies and its impact on the toxicity profile is expected under current …