Post-translational modifications in proteins: resources, tools and prediction methods

S Ramazi, J Zahiri - Database, 2021 - academic.oup.com
Posttranslational modifications (PTMs) refer to amino acid side chain modification in some
proteins after their biosynthesis. There are more than 400 different types of PTMs affecting …

Anti-cancer peptides: classification, mechanism of action, reconstruction and modification

M Xie, D Liu, Y Yang - Open biology, 2020 - royalsocietypublishing.org
Anti-cancer peptides (ACPs) are a series of short peptides composed of 10–60 amino acids
that can inhibit tumour cell proliferation or migration, or suppress the formation of tumour …

Prebiotic peptides: Molecular hubs in the origin of life

M Frenkel-Pinter, M Samanta, G Ashkenasy… - Chemical …, 2020 - ACS Publications
The fundamental roles that peptides and proteins play in today's biology makes it almost
indisputable that peptides were key players in the origin of life. Insofar as it is appropriate to …

Engineering extracellular vesicles enriched with palmitoylated ACE2 as COVID‐19 therapy

F Xie, P Su, T Pan, X Zhou, H Li, H Huang… - Advanced …, 2021 - Wiley Online Library
Abstract Angiotensin converting enzyme 2 (ACE2) is a key receptor present on cell surfaces
that directly interacts with the viral spike (S) protein of the severe acute respiratory syndrome …

Factors affecting the physical stability (aggregation) of peptide therapeutics

KL Zapadka, FJ Becher… - Interface …, 2017 - royalsocietypublishing.org
The number of biological therapeutic agents in the clinic and development pipeline has
increased dramatically over the last decade and the number will undoubtedly continue to …

[图书][B] Amino acids: biochemistry and nutrition

G Wu - 2021 - taylorfrancis.com
Following its predecessor, the second edition of Amino Acids: Biochemistry and Nutrition
presents exhaustive coverage of amino acids in the nutrition, metabolism and health of …

Studies on the mechanism of general anesthesia

MA Pavel, EN Petersen, H Wang… - Proceedings of the …, 2020 - National Acad Sciences
Inhaled anesthetics are a chemically diverse collection of hydrophobic molecules that
robustly activate TWIK-related K+ channels (TREK-1) and reversibly induce loss of …

The Receptor-Like Cytoplasmic Kinase STRK1 Phosphorylates and Activates CatC, Thereby Regulating H2O2 Homeostasis and Improving Salt Tolerance in Rice

YB Zhou, C Liu, DY Tang, L Yan, D Wang… - The Plant …, 2018 - academic.oup.com
Salt stress can significantly affect plant growth and agricultural productivity. Receptor-like
kinases (RLKs) are believed to play essential roles in plant growth, development, and …

Molecular mechanisms of phenotypic variability in monogenic autoinflammatory diseases

I Aksentijevich, O Schnappauf - Nature Reviews Rheumatology, 2021 - nature.com
Monogenic autoinflammatory diseases are a group of rheumatologic disorders caused by
dysregulation in the innate immune system. The molecular mechanisms of these disorders …

CD36 in chronic kidney disease: novel insights and therapeutic opportunities

X Yang, DM Okamura, X Lu, Y Chen… - Nature Reviews …, 2017 - nature.com
CD36 (also known as scavenger receptor B2) is a multifunctional receptor that mediates the
binding and cellular uptake of long-chain fatty acids, oxidized lipids and phospholipids …