The emergence of adaptive laboratory evolution as an efficient tool for biological discovery and industrial biotechnology
Harnessing the process of natural selection to obtain and understand new microbial
phenotypes has become increasingly possible due to advances in culturing techniques …
phenotypes has become increasingly possible due to advances in culturing techniques …
[HTML][HTML] Review of second generation bioethanol production from residual biomass
K Robak, M Balcerek - Food technology and biotechnology, 2018 - ncbi.nlm.nih.gov
In the context of climate change and the depletion of fossil fuels, there is a great need for
alternatives to petroleum in the transport sector. This review provides an overview of the …
alternatives to petroleum in the transport sector. This review provides an overview of the …
Engineering co-utilization of glucose and xylose for chemical overproduction from lignocellulose
J Gao, W Yu, Y Li, M Jin, L Yao, YJ Zhou - Nature Chemical Biology, 2023 - nature.com
Bio-refining lignocellulose could provide a sustainable supply of fuels and fine chemicals;
however, the challenges associated with the co-utilization of xylose and glucose typically …
however, the challenges associated with the co-utilization of xylose and glucose typically …
Big data mining, rational modification, and ancestral sequence reconstruction inferred multiple xylose isomerases for biorefinery
S Chen, Z Xu, B Ding, Y Zhang, S Liu, C Cai, M Li… - Science …, 2023 - science.org
The isomerization of xylose to xylulose is considered the most promising approach to initiate
xylose bioconversion. Here, phylogeny-guided big data mining, rational modification, and …
xylose bioconversion. Here, phylogeny-guided big data mining, rational modification, and …
[HTML][HTML] Adaptive laboratory evolution–principles and applications for biotechnology
M Dragosits, D Mattanovich - Microbial cell factories, 2013 - Springer
Adaptive laboratory evolution is a frequent method in biological studies to gain insights into
the basic mechanisms of molecular evolution and adaptive changes that accumulate in …
the basic mechanisms of molecular evolution and adaptive changes that accumulate in …
Process design and economics for the conversion of lignocellulosic biomass to hydrocarbons: dilute-acid and enzymatic deconstruction of biomass to sugars and …
This report describes one potential conversion process to hydrocarbon products by way of
biological conversion of lingnocellulosic-dervied sugars. The process design converts …
biological conversion of lingnocellulosic-dervied sugars. The process design converts …
[HTML][HTML] Selection of chromosomal DNA libraries using a multiplex CRISPR system
The directed evolution of biomolecules to improve or change their activity is central to many
engineering and synthetic biology efforts. However, selecting improved variants from gene …
engineering and synthetic biology efforts. However, selecting improved variants from gene …
[HTML][HTML] Xylose Fermentation by Saccharomyces cerevisiae: Challenges and Prospects
DN Moysés, VCB Reis, JRM Almeida… - International Journal of …, 2016 - mdpi.com
Many years have passed since the first genetically modified Saccharomyces cerevisiae
strains capable of fermenting xylose were obtained with the promise of an environmentally …
strains capable of fermenting xylose were obtained with the promise of an environmentally …
Microfluidic high-throughput culturing of single cells for selection based on extracellular metabolite production or consumption
Phenotyping single cells based on the products they secrete or consume is a key bottleneck
in many biotechnology applications, such as combinatorial metabolic engineering for the …
in many biotechnology applications, such as combinatorial metabolic engineering for the …
[HTML][HTML] Production of fuels and chemicals from xylose by engineered Saccharomyces cerevisiae: a review and perspective
Efficient xylose utilization is one of the most important pre-requisites for developing an
economic microbial conversion process of terrestrial lignocellulosic biomass into biofuels …
economic microbial conversion process of terrestrial lignocellulosic biomass into biofuels …