Therapies with genetically modified T cells that express chimeric antigen receptors (CARs)
specific for CD19 or B cell maturation antigen (BCMA) are approved to treat certain B cell …

The development of single-cell and spatial transcriptomics methods was instrumental in the
conception of the Human Cell Atlas initiative, which aims to generate an integrated map of …

Extracellular vesicles (EVs) are biological nanoparticles that promote intercellular
communication by delivering bioactive cargo over short and long distances. Short-distance …

Forming the inner layer of the vascular system, endothelial cells (ECs) facilitate a multitude
of crucial physiological processes throughout the body. Vascular ECs enable the vessel wall …

Detection of mismatched human leukocyte antigens by adaptive immune cells is considered
as the main cause of transplant rejection, leading to either T-cell mediated rejection or …

The field of single-cell genomics and spatial technologies is rapidly evolving and has
already provided unprecedented insights into complex tissues. Major advances have been …

Over the past decades, there has been an exponential increase in the development of
preclinical and clinical nanodelivery systems, and recently, an accelerating demand to …

Chimeric antigen receptor T (CAR-T) cell therapy is a promising and precise targeted
therapy for cancer that has demonstrated notable potential in clinical applications. However …

Targeting angiogenesis has remained one of the important aspects in disease biology in
general and cancer in particular. Currently (June 2023), over 593 clinical trials have been …

The kidney is a highly metabolic organ and requires a large amount of ATP to maintain its
filtration-reabsorption function, and mitochondrial fatty acid β-oxidation serves as the main …