Immune cells are responsible for pathogen detection and elimination, as well as for
signaling to other cells the presence of potential danger. In order to mount an efficient …

Memory T cells that mediate fast and effective protection against reinfections are usually
generated upon recognition on foreign Ags. However, a “memory-like” T-cell population …

The most effective responses to intracellular pathogens have a breadth of T-cell clones with
different affinities for their cognate peptide, and a diversity of functional phenotypes, from …

Parasitic helminths induce the production of interleukin (IL)-4 which causes the expansion of
virtual memory CD8+ T cells (TVM), a cell subset contributing to the control of viral …

Human biological ageing comprises the molecular and physiological changes that
negatively affect homeostasis with age and are strongly associated with susceptibility to …

Did you experience working in a country with more than half year raining and half year off-
work? Did you work without sun whole day? Did you experience that doing a big experiment …

Over time, the human organism is exposed to an increasing number of pathogens, which
reduces the reserve of naïve CD8+ T cells. The overall result is maladaptive protection …

Immune complications like graft failure are disproportionately associated with umbilical cord
blood (UCB) transplants that limits its clinical use. Excessive activation of donor graft derived …

Two viral agents, human immunodeficiency virus (HIV) and severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), are responsible for two biggest pandemics that …

CD8 T cells mediate a critical component of immunity against foreign pathogens,
transformed cells, and self-antigens in the settings of chronic infection, cancer, and …