Cervical cancer is a common and fatal malignancy of the female reproductive system.
Human papillomavirus (HPV) is the primary causal agent for cervical cancer, but HPV …

Human papillomaviruses (HPV) are the causative agents of cervical cancers. The infectious
HPV life cycle is closely linked to the differentiation state of the host epithelia, with viral …

We have previously reported on a system for large-scale molecular virus screening of
clinical samples. As part of an effort to systematically search for unrecognized human …

Members of the interferon-regulatory factor (IRF) proteins family were originally identified as
transcriptional regulators of the Type I interferon system. Thanks to consistent advances …

More than 100 different human papillomavirus (HPV) types have been isolated so far, and
they can be sub-grouped in cutaneous or mucosal according to their ability to infect the skin …

Deregulated expression of high-risk human papillomavirus oncogenes (E6 and E7) is a
pivotal event for pathogenesis and progression in cervical cancer. Both viral oncogenes are …

The human papillomavirus (HPV) E7 oncoprotein shares functional similarities with such
proteins as adenovirus E1A and SV40 large tumor antigen. As one of only two viral proteins …

Abstract Infection with Human papillomaviruses (HPVs) leads to the development of a wide-
range of cancers, accounting for 5% of all human cancers. A prominent example is cervical …

Ten years after the publication of the position paper “The hallmarks of cancer”(Hanahan and
Weinberg Cell 100: 57–70, 2000), it has become increasingly clear that mutated cells on …

Human papillomavirus (HPV) infection causes virtually all cases of cervical cancer, the
second most common cause of death from cancer among women worldwide. This Review …