The challenge and prospect of mRNA therapeutics landscape
Messenger RNA (mRNA)-based therapeutics hold the potential to cause a major revolution
in the pharmaceutical industry because they can be used for precise and individualized …
in the pharmaceutical industry because they can be used for precise and individualized …
[HTML][HTML] The function and clinical application of extracellular vesicles in innate immune regulation
The innate immune system plays a crucial role in the host defense against viral and
microbial infection. Exosomes constitute a subset of extracellular vesicles (EVs) that can be …
microbial infection. Exosomes constitute a subset of extracellular vesicles (EVs) that can be …
Dendritic cell-based immunotherapy: a basic review and recent advances
Dendritic cells (DCs) are considered a very promising arm to activate the immune system in
immunotherapeutic strategies against cancer. DCs are the most powerful antigen-presenting …
immunotherapeutic strategies against cancer. DCs are the most powerful antigen-presenting …
Dendritic cell therapy in cancer treatment; the state-of-the-art
M Sadeghzadeh, S Bornehdeli… - Life sciences, 2020 - Elsevier
Dendritic cells (DCs) are considered as professional antigen presenting cells (APCs),
containing a variety of subsets, that can be resident in organs or migrating among the …
containing a variety of subsets, that can be resident in organs or migrating among the …
The distinct roles of exosomes in innate immune responses and therapeutic applications in cancer
The innate immune system is one of the major constituents of the host's defense against
invading pathogens and extracellular vesicles (EVs) are involved in regulating its …
invading pathogens and extracellular vesicles (EVs) are involved in regulating its …
[HTML][HTML] Recent advances in experimental dendritic cell vaccines for cancer
The development of immunotherapeutic methods for the treatment of oncological diseases
have made it possible to improve the effectiveness of standard therapies. There was no …
have made it possible to improve the effectiveness of standard therapies. There was no …
mRNA-based dendritic cell vaccines
D Benteyn, C Heirman, A Bonehill… - Expert review of …, 2015 - Taylor & Francis
Cancer immunotherapy has been proposed as a powerful treatment modality. Active
immunotherapy aspires to stimulate the patient's immune system, particularly T cells. These …
immunotherapy aspires to stimulate the patient's immune system, particularly T cells. These …
[HTML][HTML] Dendritic cell vaccines in breast cancer: Immune modulation and immunotherapy
D Qian, J Li, M Huang, Q Cui, X Liu, K Sun - Biomedicine & …, 2023 - Elsevier
Breast cancer (BC) is the most common cancer in women worldwide. Although substantial
progress has been made in the diagnosis and treatment of breast cancer, the efficacy and …
progress has been made in the diagnosis and treatment of breast cancer, the efficacy and …
Microtubule-depolymerizing agents used in antibody–drug conjugates induce antitumor immunity by stimulation of dendritic cells
P Müller, K Martin, S Theurich, J Schreiner… - Cancer immunology …, 2014 - AACR
Antibody–drug conjugates (ADC) are emerging as powerful treatment strategies with
outstanding target-specificity and high therapeutic activity in patients with cancer …
outstanding target-specificity and high therapeutic activity in patients with cancer …
[HTML][HTML] Dendritic cells in anticancer vaccination: rationale for ex vivo loading or in vivo targeting
AV Baldin, LV Savvateeva, AV Bazhin, AA Zamyatnin Jr - Cancers, 2020 - mdpi.com
Dendritic cells (DCs) have shown great potential as a component or target in the landscape
of cancer immunotherapy. Different in vivo and ex vivo strategies of DC vaccine generation …
of cancer immunotherapy. Different in vivo and ex vivo strategies of DC vaccine generation …